Publikace

 

Seznam publikací: CLIP / spolupráce

 

2022

Zuna J, Hovorkova L, Krotka J, Koehrmann A, Bardini M, Winkowska L, Fronkova E, Alten J, Koehler R, Eckert C, Brizzolara L, Trkova M, Stuchly J, Zimmermann M, De Lorenzo P, Valsecchi MG, Conter V, Stary J, Schrappe M, Biondi A, Trka J, Zaliova M, Cazzaniga G, Cario G.

Minimal residual disease in BCR::ABL1-positive acute lymphoblastic leukemia: different significance in typical ALL and in CML-like disease.

Leukemia. 2022 Aug 6.

 

Fronkova E, Svaton M, Trka J.

Quality Control for IG /TR Marker Identification and MRD Analysis.

Methods Mol Biol. 2022;2453:91-99.

 

Svaton M, Sukova M, Sedlacek P, Skotnicova A, Vodickova E, van Wijk R, Divoka M, Mojzikova R, Kalina T, Trka J, Fronkova E, Stary J.

Hydrops fetalis and failure of hematopoietic stem cell transplantation - A long route to the diagnosis of SPTA1-associated hereditary spherocytosis.

Blood Cells Mol Dis. 2022 Apr 16;95:102664.

 

Hlozkova K, Hermanova I, Safrhansova L, Alquezar-Artieda N, Kuzilkova D, Vavrova A, Sperkova K, Zaliova M, Stary J, Trka J, Starkova J.

PTEN/PI3K/Akt pathway alters the sensitivity of T-cell acute lymphoblastic leukemia to L-asparaginase

Sci Rep. 2022 Mar 8;12(1)

 

Fejtkova M, Sukova M, Hlozkova K, Skvarova Kramarzova K, Rackova M, Jakubec D, Bakardjieva M, Bloomfield M, Klocperk A, Parackova Z, Sediva A, Aluri J, Novakova M, Kalina T, Fronkova E, Hrusak O, Malcova H, Sedlacek P, Liba Z, Kudr M, Stary J, Cooper MA, Svaton M, Kanderova V.

TLR8/TLR7 dysregulation due to a novel TLR8 mutation causes severe autoimmune hemolytic anemia and autoinflammation in identical twins

Am J Hematol. 2022 Mar 1;97(3)

 

Kužílková D, Puñet-Ortiz J, Aui PM, Fernández J, Fišer K, Engel P, van Zelm MC, Kalina T.

Standardization of Workflow and Flow Cytometry Panels for Quantitative Expression Profiling of Surface Antigens on Blood Leukocyte Subsets: An HCDM CDMaps Initiative

Front Immunol. 2022 Feb 11

 

Kiss I, Kuhn M, Hrusak K, Buchler B, Boublikova L, Buchler T.

Insomnia in patients treated with checkpoint inhibitors for cancer: A meta-analysis.

Front Oncol. 2022 Aug 2;12:946307.

 

Csomos K, Ujhazi B, Blazso P, Herrera JL, Tipton CM, Kawai T, Gordon S, Ellison M, Wu K, Stowell M, Haynes L, Cruz R, Zakota B, Nguyen J, Altrich M, Geier CB, Sharapova S, Dasso JF, Leiding JW, Smith G, Al-Herz W, de Barros Dorna M, Fadugba O, Fronkova E, Kanderova V, Svaton M, Henrickson SE, Hernandez JD, Kuijpers T, Kandilarova SM, Naumova E, Milota T, Sediva A, Moshous D, Neven B, Saco T, Sargur R, Savic S, Sleasman J, Sunkersett G, Ward BR, Komatsu M, Pittaluga S, Kumanovics A, Butte MJ, Cancro MP, Pillai S, Meffre E, Notarangelo LD, Walter JE.

Partial RAG deficiency in humans induces dysregulated peripheral lymphocyte development and humoral tolerance defect with accumulation of T-bet+ B cells.

Nat Immunol. 2022 Jul 28. Online ahead of print.

 

Boublikova L, Kramarzova KS, Zwyrtkova M, Bakardjieva-Mihaylova V, Stuchly J, Rosova B, Kolostova K, Sonsky J, Kindlova E, Zachoval R, Buchler T, Trka J.

The clinical value of circulating free tumor DNA in testicular germ cell tumor patients.

Urol Oncol. 2022 Jun 18:S1078-1439(22)00150-8.

 

Salmon M, White HE, Zizkova H, Gottschalk A, Motlova E, Cerveira N, Colomer D, Coriu D, Franke GN, Gottardi E, Izzo B, Jurcek T, Lion T, Schäfer V, Venturi C, Vigneri P, Zawada M, Zuna J, Hovorkova L, Koblihova J, Klamova H, Markova MS, Srbova D, Benesova A, Polivkova V, Zackova D, Mayer J, Roeder I, Glauche I, Ernst T, Hochhaus A, Polakova KM, Cross NCP.

Impact of BCR::ABL1 transcript type on RT-qPCR amplification performance and molecular response to therapy.

Leukemia. 2022 Jun 8.

 

Pokorna P, Lakka Klement G, Vasikova A, Kanderova V, Jezova M, Noskova K, Mudry P, Kyr M, Merta T, Bajciova V, Krenova Z, Palova H, Valik D, Zdrazilova Dubska L, Slaby O, Sterba J.

Minimal Residual Disease-Guided Intermittent Dosing in Patients With Cancer: Successful Treatment of Chemoresistant Anaplastic Large Cell Lymphoma Using Intermittent Lorlatinib Dosing.

JCO Precis Oncol. 2022 Jun;6:e2100525.

 

Venn NC, Huang L, Hovorková L, Muskovic W, Wong M, Law T, Heatley SL, Khaw SL, Revesz T, Dalla Pozza L, Shaw PJ, Fraser C, Moore AS, Cross S, Bendak K, Norris MD, Henderson MJ, White DL, Cowley MJ, Trahair TN, Zuna J, Sutton R.

Measurable residual disease analysis in paediatric acute lymphoblastic leukaemia patients with ABL-class fusions.

Br J Cancer. 2022 Jun 1.

 

Mersakova S, Janikova K, Kalman M, Marcinek J, Grendar M, Vojtko M, Kycina R, Pindura M, Janik J, Mikolajcik P, Gabonova E, Laca L, Mejstrikova E, Halasova E, Strnadel J, Lasabova Z.

Cancer stem cell marker expression and methylation status in patients with colorectal cancer.

Oncol Lett. 2022 May 27;24(1):231.

 

Jakša R, Karolová J, Svatoň M, Kazantsev D, Grajciarová M, Pokorná E, Tonar Z, Klánová M, Winkowska L, Maláriková D, Vočková P, Forsterová K, Renešová N, Dolníková A, Nožičková K, Dundr P, Froňková E, Trněný M, Klener P.

Complex genetic and histopathological study of 15 patient-derived xenografts of aggressive lymphomas.

Lab Invest. 2022 Apr 29.

 

Deyà-Martínez A, Rivière JG, Roxo-Junior P, Ramakers J, Bloomfield M, Guisado Hernandez P, Blanco Lobo P, Abu Jamra SR, Esteve-Sole A, Kanderova V, García-García A, Lopez-Corbeto M, Martinez Pomar N, Martín-Nalda A, Alsina L, Neth O, Olbrich P.

Impact of JAK Inhibitors in Pediatric Patients with STAT1 Gain of Function (GOF) Mutations-10 Children and Review of the Literature.

J Clin Immunol. 2022 Apr 29.

 

Locatelli F, Eckert C, Hrusak O, Buldini B, Sartor M, Zugmaier G, Zeng Y, Pilankar D, Morris J, von Stackelberg A.

Blinatumomab overcomes poor prognostic impact of measurable residual disease in pediatric high-risk first relapse B-cell precursor acute lymphoblastic leukemia.

Pediatr Blood Cancer. 2022 Apr 28:e29715.

 

Brouwer N, Matarraz S, Nierkens S, Hofmans M, Nováková M, da Costa ES, Fernandez P, Bras AE, de Mello FV, Mejstrikova E, Philippé J, Grigore GE, Pedreira CE, van Dongen JJM, Orfao A, van der Velden VHJ, On Behalf Of The EuroFlow Consortium.

Immunophenotypic Analysis of Acute Megakaryoblastic Leukemia: A EuroFlow Study.

Cancers (Basel). 2022 Mar 21;14(6):1583.

 

Egg D, Rump IC, Mitsuiki N, Rojas-Restrepo J, Maccari ME, Schwab C, Gabrysch A, Warnatz K, Goldacker S, Patiño V, Wolff D, Okada S, Hayakawa S, Shikama Y, Kanda K, Imai K, Sotomatsu M, Kuwashima M, Kamiya T, Morio T, Matsumoto K, Mori T, Yoshimoto Y, Dybedal I, Kanariou M, Kucuk ZY, Chapdelaine H, Petruzelkova L, Lorenz HM, Sullivan KE, Heimall J, Moutschen M, Litzman J, Recher M, Albert MH, Hauck F, Seneviratne S, Pachlopnik Schmid J, Kolios A, Unglik G, Klemann C, Snapper S, Giulino-Roth L, Svaton M, Platt CD, Hambleton S, Neth O, Gosse G, Reinsch S, Holzinger D, Kim YJ, Bakhtiar S, Atschekzei F, Schmidt R, Sogkas G, Chandrakasan S, Rae W, Derfalvi B, Marquart HV, Ozen A, Kiykim A, Karakoc-Aydiner E, Králíčková P, de Bree G, Kiritsi D, Seidel MG, Kobbe R, Dantzer J, Alsina L, Armangue T, Lougaris V, Agyeman P, Nyström S, Buchbinder D, Arkwright PD, Grimbacher B.

Therapeutic options for CTLA-4 insufficiency.

J Allergy Clin Immunol. 2022 Feb;149(2):736-746.

 

2021

Kuzilková D, Bugarin C, Rejlova K, Schulz AR, Mei HE, Paganin M, Biffi A, Biondi A, Kalina T, Gaipa G.

Either IL-7 activation of JAK-STAT or BEZ inhibition of PI3K-AKT-mTOR pathways dominates the single-cell phosphosignature of ex vivo treated pediatric T-cell acute lymphoblastic leukemia cells.

Haematologica. 2021 Oct 21.

 

Kanderova V, Svobodova T, Borna S, Fejtkova M, Martinu V, Paderova J, Svaton M, Kralova J, Fronkova E, Klocperk A, Pruhova S, Lee-Kirsch MA, Hornofova L, Koblizek M, Novak P, Zimmermannova O, Parackova Z, Sediva A, Kalina T, Janda A, Kayserova J, Dvorakova M, Macek M, Pohunek P, Sedlacek P, Poh A, Ernst M, Brdicka T, Hrusak O, Lebl J.

Early-onset pulmonary and cutaneous vasculitis driven by constitutively active SRC-family kinase HCK

J Allergy Clin Immunol. 2021 Sep 15:S0091-6749(21)01395-6.

 

Zaliova M, Winkowska L, Stuchly J, Fiser K, Triska P, Zwyrtkova M, Hrusak O, Starkova J, Sramkova L, Stary J, Trka J, Zuna J.

Novel class of ZNF384 aberrations in acute leukemia

Blood Adv. 2021 Sep 16:bloodadvances.2021005318.

 

Mejstrikova E, Klinger M, Markovic A, Zugmaier G, Locatelli F.

CD19 expression in pediatric patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia pre- and post-treatment with blinatumomab

Pediatr Blood Cancer. 2021 Sep 14:e29323.

Lukes J, Wolthers BO, Altaf Raja R, Uhrinova K, Skvarova Kramarzova K, Hermanova I, Simcikova M, Kicko P, Zaliova M, Sramkova L, Stary J, Trka J, Schmiegelow K, Starkova.

J.Pancreatitis-associated protein as an early marker of asparaginase-associated pancreatitis

Leuk Lymphoma. 2021 Aug 9:1-5.

 

Verbeek MWC, Buracchi C, Laqua A, Nierkens S, Sedek L, Flores-Montero J, Hofmans M, Sobral de Costa E, Nováková M, Mejstrikova E, Barrena S, Kohlscheen S, Szczepanowski M, Kulis J, Oliveira E, Jugooa R, de Jong AX, Szczepanski T, Philippé J, van Dongen JJM, Orfao A, Brüggemann M, Gaipa G, van der Velden VHJ.

Flow cytometric minimal residual disease assessment in B-cell precursor acute lymphoblastic leukaemia patients treated with CD19-targeted therapies - a EuroFlow study

Br J Haematol. 2021 Dec 8.

 

Maurer-Granofszky M, Schumich A, Buldini B, Gaipa G, Kappelmayer J, Mejstrikova E, Karawajew L, Rossi J, Suzan AÇ, Agriello E, Anastasiou-Grenzelia T, Barcala V, Barna G, Batinić D, Bourquin JP, Brüggemann M, Bukowska-Strakova K, Burnusuzov H, Carelli D, Deniz G, Dubravčić K, Feuerstein T, Gaillard MI, Galeano A, Giordano H, Gonzalez A, Groeneveld-Krentz S, Hevessy Z, Hrusak O, Iarossi MB, Jáksó P, Kloboves Prevodnik V, Kohlscheen S, Kreminska E, Maglia O, Malusardi C, Marinov N, Martin BM, Möller C, Nikulshin S, Palazzi J, Paterakis G, Popov A, Ratei R, Rodríguez C, Sajaroff EO, Sala S, Samardzija G, Sartor M, Scarparo P, Sędek Ł, Slavkovic B, Solari L, Svec P, Szczepanski T, Taparkou A, Torrebadell M, Tzanoudaki M, Varotto E, Vernitsky H, Attarbaschi A, Schrappe M, Conter V, Biondi A, Felice M, Campbell M, Kiss C, Basso G, Dworzak MN, On Behalf Of I-Bfm-Flow-Network.

An Extensive Quality Control and Quality Assurance (QC/QA) Program Significantly Improves Inter-Laboratory Concordance Rates of Flow-Cytometric Minimal Residual Disease Assessment in Acute Lymphoblastic Leukemia: An I-BFM-FLOW-Network Report

Cancers (Basel). 2021 Dec 6;13(23):6148.

 

Permikin Z, Popov A, Verzhbitskaya T, Riger T, Plekhanova O, Makarova O, Froňková E, Trka J, Meyer C, Marschalek R, Tsaur G, Fechina L.

Lineage switch to acute myeloid leukemia during induction chemotherapy for early T-cell precursor acute lymphoblastic leukemia with the translocation t(6;11)(q27;q23)/KMT2A-AFDN: A case report

Leuk Res. 2021 Nov 25;112:106758.

 

Havlin J, Skotnicova A, Dvorackova E, Hubacek P, Svorcova M, Lastovicka J, Sediva A, Kalina T, Lischke R.

Impaired Humoral Response to Third Dose of BNT162b2 mRNA COVID-19 Vaccine Despite Detectable Spike Protein-specific T cells in Lung Transplant Recipients

Transplantation. 2021 Nov 24.

 

Böttcher S, Engelmann R, Grigore G, Fernandez PC, Caetano J, Flores-Montero J, van der Velden VHJ, Novakova M, Philippé J, Ritgen M, Burgos L, Lecrevisse QA, Lange S, Kalina T, Verde J, Fluxa R, van Dongen JJM, Pedreira CE, Orfao A.

Expert-independent classification of mature B-cell neoplasms using standardized flow cytometry: a multicentric study

Blood Adv. 2021 Nov 23

 

Šálek C, Folber F, Froňková E, Pecherková P, Jelínková H, Hrabovský Š, Horáček JM, Cetkovský P, Mayer J, Trka J, Doubek M; Czech Leukemia Study Group - for Life (CELL).

Low levels of minimal residual disease after induction chemotherapy for BCR-ABL1-negative acute lymphoblastic leukaemia in adults are clinically relevant

Br J Haematol. 2021 Nov 23.

 

Modrák M, Bürkner PC, Sieger T, Slisz T, Vašáková M, Mesežnikov G, Casas-Mendez LF, Vajter J, Táborský J, Kubricht V, Suk D, Horejsek J, Jedlička M, Mifková A, Jaroš A, Kubiska M, Váchalová J, Šín R, Veverková M, Pospíšil Z, Vohryzková J, Pokrievková R, Hrušák K, Christozova K, Leos-Barajas V, Fišer K, Hyánek T.

Disease progression of 213 patients hospitalized with Covid-19 in the Czech Republic in March-October 2020: An exploratory analysis

PLoS One. 2021 Oct 6;16(10):e0245103.

 

Bataller A, Guijarro F, Caye A, Strullu M, Sterin A, Molina O, Chevallier P, Zaliova M, Zuna J, Mozas P, Magnano L, Grardel N, Cornillet-Lefebvre P, Fu JF, Shih LY, Boneva T, Nacheva EP, Beà S, López-Guerra M, Bueno C, Menéndez P, Esteve J, Larghero P, Meyer C, Marschalek R.

KMT2A-CBL rearrangements in acute leukemias: clinical characteristics and genetic breakpoints

Blood Adv. 2021 Oct 1

 

Curik N, Polivkova V, Burda P, Koblihova J, Laznicka A, Kalina T, Kanderova V, Brezinova J, Ransdorfova S, Karasova D, Rejlova K, Bakardjieva M, Kuzilkova D, Kundrat D, Linhartova J, Klamova H, Salek C, Klener P, Hrusak O, Machova Polakova K.

Somatic Mutations in Oncogenes Are in Chronic Myeloid Leukemia Acquired De Novo via Deregulated Base-Excision Repair and Alternative Non-Homologous End Joining

Front Oncol. 2021 Sep 20;11:744373.

 

Lühmann JL, Stelter M, Wolter M, Kater J, Lentes J, Bergmann AK, Schieck M, Göhring G, Möricke A, Cario G, Žaliová M, Schrappe M, Schlegelberger B, Stanulla M, Steinemann D.

The Clinical Utility of Optical Genome Mapping for the Assessment of Genomic Aberrations in Acute Lymphoblastic Leukemia

Cancers (Basel). 2021 Aug 30;13(17):4388.

 

Bloomfield M, Klocperk A, Zachova R, Milota T, Kanderova V, Sediva A.

Natural Course of Activated Phosphoinositide 3-Kinase Delta Syndrome in Childhood and Adolescence

Front Pediatr. 2021 Jul 19;9:697706.

 

Boer JM, Valsecchi MG, Hormann FM, Antić Ž, Zaliova M, Schwab C, Cazzaniga G, Arfeuille C, Cavé H, Attarbaschi A, Strehl S, Escherich G, Imamura T, Ohki K, Grüber TA, Sutton R, Pastorczak A, Lammens T, Lambert F, Li CK, Carrillo de Santa Pau E, Hoffmann S, Möricke A, Harrison CJ, Den Boer ML, De Lorenzo P, Stam RW, Bergmann AK, Pieters R.

Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study

Leukemia. 2021 Jul 1

 

Havlin J, Svorcova M, Dvorackova E, Lastovicka J, Lischke R, Kalina T, Hubacek P.

Immunogenicity of BNT162b2 mRNA COVID-19 vaccine and SARS-CoV-2 infection in lung transplant recipients

J Heart Lung Transplant. 2021 May 21

 

Sági JC, Gézsi A, Egyed B, Jakab Z, Benedek N, Attarbaschi A, Köhrer S, Sipek J, Winkowska L, Zaliova M, Anastasopoulou S, Wolthers BO, Ranta S, Szalai C, Kovács GT, Semsei ÁF, Erdélyi DJ.

Pharmacogenetics of the Central Nervous System-Toxicity and Relapse Affecting the CNS in Pediatric Acute Lymphoblastic Leukemia

Cancers (Basel). 2021 May 12;13(10):2333.

 

Uhlířová J, Šebestová L, Fišer K, Sieger T, Fišerová J, Hozák P.

Nucleoporin TPR Affects C2C12 Myogenic Differentiation via Regulation of Myh4 Expression

Cells. 2021 May 21;10(6):1271.

 

Hirabayashi S, Butler ER, Ohki K, Kiyokawa N, Bergmann AK, Möricke A, Boer JM, Cavé H, Cazzaniga G, Yeoh AEJ, Sanada M, Imamura T, Inaba H, Mullighan C, Loh ML, Norén-Nyström U, Pastorczak A, Shih LY, Zaliova M, Pui CH, Haas OA, Harrison CJ, Moorman AV, Manabe A.

Clinical characteristics and outcomes of B-ALL with ZNF384 rearrangements: a retrospective analysis by the Ponte di Legno Childhood ALL Working Group

Leukemia. 2021 Mar 10.

 

Locatelli F, Zugmaier G, Rizzari C, Morris JD, Gruhn B, Klingebiel T, Parasole R, Linderkamp C, Flotho C, Petit A, Micalizzi C, Mergen N, Mohammad A, Kormany WN, Eckert C, Möricke A, Sartor M, Hrusak O, Peters C, Saha V, Vinti L, von Stackelberg A.

Effect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial

JAMA. 2021 Mar 2;325(9):843-854.

 

Del Pino-Molina L, López-Granados E, Lecrevisse Q, Torres Canizales J, Pérez-Andrés M, Blanco E, Wentink M, Bonroy C, Nechvatalova J, Milota T, Kienzler AK, Philippé J, Sousa AE, van der Burg M, Kalina T, van Dongen JJM, Orfao A.

Dissection of the Pre-Germinal Center B-Cell Maturation Pathway in Common Variable Immunodeficiency Based on Standardized Flow Cytometric EuroFlow Tools.

Front Immunol. 2021 Feb 17;11:603972.

 

van der Velden VHJ, Brüggemann M, Cazzaniga G, Scheijen B, Tops B, Trka J, Pal K, Hänzelmann S, Fazio G, Songia S, Langerak AW, Darzentas N; EuroMRD; EuroClonality-NGS Working Group.

Potential and pitfalls of whole transcriptome-based immunogenetic marker identification in acute lymphoblastic leukemia; a EuroMRD and EuroClonality-NGS Working Group study.

Leukemia. 2021 Mar;35(3):924-928.

 

Zeisig BB, Fung TK, Zarowiecki M, Tsai CT, Luo H, Stanojevic B, Lynn C, Leung AYH, Zuna J, Zaliova M, Bornhauser M, von Bonin M, Lenhard B, Huang S, Mufti GJ, So CWE.

Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia.

Sci Transl Med. 2021 Feb 24;13(582):eabc4822.

 

Stutterheim J, van der Sluis IM, de Lorenzo P, Alten J, Ancliffe P, Attarbaschi A, Brethon B, Biondi A, Campbell M, Cazzaniga G, Escherich G, Ferster A, Kotecha RS, Lausen B, Li CK, Lo Nigro L, Locatelli F, Marschalek R, Meyer C, Schrappe M, Stary J, Vora A, Zuna J, van der Velden VHJ, Szczepanski T, Valsecchi MG, Pieters R.

Clinical Implications of Minimal Residual Disease Detection in Infants With KMT2A-Rearranged Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol.

J Clin Oncol. 2021 Jan 6

 

Maccari ME, Fuchs S, Kury P, Andrieux G, Völkl S, Bengsch B, Lorenz MR, Heeg M, Rohr J, Jägle S, Castro CN, Groß M, Warthorst U, König C, Fuchs I, Speckmann C, Thalhammer J, Kapp FG, Seidel MG, Dückers G, Schönberger S, Schütz C, Führer M, Kobbe R, Holzinger D, Klemann C, Smisek P, Owens S, Horneff G, Kolb R, Naumann-Bartsch N, Miano M, Staniek J, Rizzi M, Kalina T, Schneider P, Erxleben A, Backofen R, Ekici A, Niemeyer CM, Warnatz K, Grimbacher B, Eibel H, Mackensen A, Frei AP, Schwarz K, Boerries M, Ehl S, Rensing-Ehl A.

A distinct CD38+CD45RA+ population of CD4+, CD8+, and double-negative T cells is controlled by FAS

J Exp Med. 2021 Feb 1;218(2)

 

den Boer ML, Cario G, Moorman AV, Boer JM, de Groot-Kruseman HA, Fiocco M, Escherich G, Imamura T, Yeoh A, Sutton R, Dalla-Pozza L, Kiyokawa N, Schrappe M, Roberts KG, Mullighan CG, Hunger SP, Vora A, Attarbaschi A, Zaliova M, Elitzur S, Cazzaniga G, Biondi A, Loh ML, Pieters R; Ponte di Legno Childhood ALL Working Group.

Outcomes of paediatric patients with B-cell acute lymphocytic leukaemia with ABL-class fusion in the pre-tyrosine-kinase inhibitor era: a multicentre, retrospective, cohort study

Lancet Haematol. 2021 Jan;8(1):e55-e66

 

2020

Lukes J Jr, Winkowska L, Zwyrtkova M, Starkova J, Sramkova L, Stary J, Trka J, Zuna J, Zaliova M.

Identification of Fusion Gene Breakpoints is Feasible and Facilitates Accurate Sensitive Minimal Residual Disease Monitoring on Genomic Level in Patients With PML-RARA, CBFB-MYH11, and RUNX1-RUNX1T1

Hemasphere. 2020 Nov 10;4(6)

 

Vakrmanova B, Fronkova E, Zuna J, Janotova I, Jabali Y, Rezkova Reznickova L, Zdrahalova K, Trka J, Stary J, Hrusak O, Mejstrikova E.

Blast clearance after one week of corticosteroids correlates with outcome and genetics but does not justify adding a residual disease time point in acute lymphoblastic leukemia treatment

Leuk Lymphoma. 2020 Oct 29:1-3.

 

Sramkova L, Cermakova J, Kutkova K, Zemanova Z, Pavlicek P, Zuna J, Stary J, Zaliova M.

Rapidly progressing acute myeloid leukemia with KAT6A-LEUTX fusion in a newborn

Pediatr Blood Cancer. 2020 Aug 11:e28663

 

Novakova M, Zaliova M, Fiser K, Vakrmanova B, Slamova L, Musilova A, Brüggemann M, Ritgen M, Fronkova E, Kalina T, Stary J, Winkowska L, Svec P, Kolenova A, Stuchly J, Zuna J, Trka J, Hrusak O, Mejstrikova E.

DUX4r, ZNF384r and PAX5-P80R mutated B-cell precursor acute lymphoblastic leukemia frequently undergo monocytic switch

Haematologica. 2020 Jul 9

 

Hlozkova K, Pecinova A, Alquezar-Artieda N, Pajuelo-Reguera D, Simcikova M, Hovorkova L, Rejlova K, Zaliova M, Mracek T, Kolenova A, Stary J, Trka J, Starkova J.

Metabolic profile of leukemia cells influences treatment efficacy of L-asparaginase

BMC Cancer. 2020 Jun 5;20(1):526.

 

Zaliova M, Potuckova E, Lukes J Jr, Winkowska L, Starkova J, Janotova I, Sramkova L, Stary J, Zuna J, Stanulla M, Zimmermann M, Bornhauser B, Bourquin JP, Eckert C, Cario G, Trka J.

Frequency and prognostic impact of ZEB2 H1038 and 1072 mutations in childhood B-other acute lymphoblastic leukemia

Haematologica. 2020 Jun 4

 

Kalina T, Bakardjieva M, Blom M, Perez-Andres M, Barendregt B, Kanderová V, Bonroy C, Philippé J, Blanco E, Pico-Knijnenburg I, Paping JHMP, Wolska-Kuśnierz B, Pac M, Tkazcyk J, Haerynck F, Akar HH, Formánková R, Freiberger T, Svatoň M, Šedivá A, Arriba-Méndez S, Orfao A, van Dongen JJM, van der Burg M.

EuroFlow Standardized Approach to Diagnostic Immunopheneotyping of Severe PID in Newborns and Young Children.

Front Immunol. 2020 Mar 19;11:371.

 

Kalina T, Abraham RS, Rizzi M, van der Burg M.

Editorial: Application of Cytometry in Primary Immunodeficiencies.

Front Immunol. 2020 Mar 19;11:463.

 

Svaton M, Skvarova Kramarzova K, Kanderova V, Mancikova A, Smisek P, Jesina P, Krijt J, Stiburkova B, Dobrovolny R, Sokolova J, Bakardjieva-Mihaylova V, Vodickova E, Rackova M, Stuchly J, Kalina T, Stary J, Trka J, Fronkova E, Kozich V.

A homozygous deletion in the SLC19A1 gene as a cause of folate-dependent recurrent megaloblastic anemia.

Blood. 2020 Apr 10.

 

Hrusak O, Kalina T, Wolf J, Balduzzi A, Provenzi M, Rizzari C, Rives S, Del Pozo Carlavilla M, Alonso MEV, Domínguez-Pinilla N, Bourquin JP, Schmiegelow K, Attarbaschi A, Grillner P, Mellgren K, van der Werff Ten Bosch J, Pieters R, Brozou T, Borkhardt A, Escherich G, Lauten M, Stanulla M, Smith O, Yeoh AEJ, Elitzur S, Vora A, Li CK, Ariffin H, Kolenova A, Dallapozza L, Farah R, Lazic J, Manabe A, Styczynski J, Kovacs G, Ottoffy G, Felice MS, Buldini B, Conter V, Stary J, Schrappe M.

Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment.

Eur J Cancer. 2020 Apr 7;132:11-16

 

Lukes J Jr, Danek P, Alejo-Valle O, Potuckova E, Gahura O, Heckl D, Starkova J, Stary J, Mejstrikova E, Alberich-Jorda M, Zuna J, Trka J, Klusmann JH, Zaliova M.

Chromosome 21 gain is dispensable for transient myeloproliferative disorder driven by a novel GATA1 mutation.

Leukemia. 2020 Feb 24

 

Bras AE, Osmani Z, de Haas V, Jongen-Lavrencic M, Te Marvelde JG, Zwaan CM, Mejstrikova E, Fernandez P, Szczepanski T, Orfao A, van Dongen JJM, van der Velden VHJ.

Standardised immunophenotypic analysis of myeloperoxidase in acute leukaemia

Br J Haematol. 2020 Nov 7

 

Gothe F, Hatton CF, Truong L, Klimova Z, Kanderova V, Fejtkova M, Grainger A, Bigley V, Perthen J, Mitra D, Janda A, Fronkova E, Moravcikova D, Hambleton S, Duncan CJA.

A novel case of homozygous IFNAR1 deficiency with haemophagocytic lymphohistiocytosis

Clin Infect Dis. 2020 Nov 30

 

Lhermitte L, Barreau S, Morf D, Fernandez P, Grigore G, Barrena S, de Bie M, Flores-Montero J, Brüggemann M, Mejstrikova E, Nierkens S, Burgos L, Caetano J, Gaipa G, Buracchi C, da Costa ES, Sedek L, Szczepański T, Aanei CM, van der Sluijs-Gelling A, Delgado AH, Fluxa R, Lecrevisse Q, Pedreira CE, van Dongen JJM, Orfao A, van der Velden VHJ; EuroFlow Consortium.

Automated identification of leukocyte subsets improves standardization of database-guided expert-supervised diagnostic orientation in acute leukemia: a EuroFlow study

Mod Pathol. 2020 Sep 30

 

Wolfs TFW, Attarbaschi A, Balduzzi A, Bernardo ME, Bomken S, Borkhardt A, Bourquin JP, Dufour C, Gennery A, Grainger J, Hasle H, Hrusak O, Izraeli S, Mechinaud F, Trka J, Vormoor J.

COVID-19 - Impact on Childhood Haematology Patients

J.Hemasphere. 2020 Sep 11;4(5):e465

 

Bornhauser B, Cario G, Rinaldi A, Risch T, Rodriguez Martinez V, Schütte M, Warnatz HJ, Scheidegger N, Mirkowska P, Temperli M, Möller C, Schumich A, Dworzak M, Attarbaschi A, Brüggemann M, Ritgen M, Mejstrikova E, Hofmann A, Buldini B, Scarparo P, Basso G, Maglia O, Gaipa G, Skoblyn TL, Te Kronnie G, Vendramini E, Panzer-Grümayer R, Barz MJ, Marovca B, Hauri-Hohl M, Niggli F, Eckert C, Schrappe M, Stanulla M, Zimmermann M, Wollscheid B, Yaspo ML, Bourquin JP.

The hematopoietic stem cell marker VNN2 is associated with chemoresistance in pediatric B-cell precursor ALL

Blood Adv. 2020 Sep 8;4(17)

 

Hensler M, Kasikova L, Fiser K, Rakova J, Skapa P, Laco J, Lanickova T, Pecen L, Truxova I, Vosahlikova S, Moserova I, Praznovec I, Drochytek V, Rehackova M, Brtnicky T, Rob L, Benes V, Pistolic J, Sojka L, Ryska A, Sautes-Fridman C, Fridman WH, Galluzzi L, Spisek R, Fucikova J.

M2-like macrophages dictate clinically relevant immunosuppression in metastatic ovarian cancer

J Immunother Cancer. 2020 Aug;8(2)

 

Malarikova D, Berkova A, Obr A, Blahovcova P, Svaton M, Forsterova K, Kriegova E, Prihodova E, Pavlistova L, Petrackova A, Zemanova Z, Trneny M, Klener P.

Concurrent TP53 and CDKN2A Gene Aberrations in Newly Diagnosed Mantle Cell Lymphoma Correlate with Chemoresistance and Call for Innovative Upfront Therapy.

Cancers (Basel). 2020 Jul 31;12(8):2120.

 

Gurka J, Piherova L, Majer F, Chaloupka A, Zakova D, Pelak O, Krebsova A, Peichl P, Krejci J, Freiberger T, Melenovsky V, Kautzner J, Kalina T, Sikora J, Kubanek M.

Danon disease is an underdiagnosed cause of advanced heart failure in young female patients: a LAMP2 flow cytometric study

ESC Heart Fail. 2020 Jul 13;7(5):2534-43.

 

Novakova-Jiresova A, Kopeckova K, Boublikova L, Chloupkova R, Melichar B, Petruzelka L, Finek J, Fiala O, Grell P, Batko S, Linke Z, Kiss I, Prausova J, Buchler T.

Regorafenib for Metastatic Colorectal Cancer: An Analysis of a Registry-Based Cohort of 555 Patients

Cancer Manag Res. 2020 Jul 3;12:5365-5372.

 

Mezzatesta C, Abduli L, Guinot A, Eckert C, Schewe D, Zaliova M, Vinti L, Marovca B, Tsai YC, Jenni S, Aguade-Gorgorio J, von Stackelberg A, Schrappe M, Locatelli F, Stanulla M, Cario G, Bourquin JP, Bornhauser BC.

Repurposing anthelmintic agents to eradicate resistant leukemia

Blood Cancer J. 2020 Jun 26;10(6):72.

 

Hoffmann J, Puntmann VO, Fišer K, Rasper T, Berkowitsch A, Carerj ML, Nagel E, Dimmeler S, Zeiher AM.

Circulating Th17 and Th22 Cells Are Associated With CMR Imaging Biosignatures of Diffuse Myocardial Interstitial Remodeling in Chronic Coronary Artery Disease

Circ Res. 2020 Aug 14;127(5):699-701.

 

Kozyra EJ, Pastor VB, Lefkopoulos S, Sahoo SS, Busch H, Voss RK, Erlacher M, Lebrecht D, Szvetnik EA, Hirabayashi S, Pasaulienė R, Pedace L, Tartaglia M, Klemann C, Metzger P, Boerries M, Catala A, Hasle H, de Haas V, Kállay K, Masetti R, De Moerloose B, Dworzak M, Schmugge M, Smith O, Starý J, Mejstrikova E, Ussowicz M, Morris E, Singh P, Collin M, Derecka M, Göhring G, Flotho C, Strahm B, Locatelli F, Niemeyer CM, Trompouki E, Wlodarski MW; European Working Group of MDS in Childhood (EWOG-MDS).

Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency

Leukemia. 2020 Oct;34(10):2673-2687.

 

Kousal B, Majer F, Vlaskova H, Dvorakova L, Piherova L, Meliska M, Langrova H, Palecek T, Kubanek M, Krebsova A, Gurka J, Stara V, Michaelides M, Kalina T, Sikora J, Liskova P.

Pigmentary retinopathy can indicate the presence of pathogenic LAMP2 variants even in somatic mosaic carriers with no additional signs of Danon disease

Acta Ophthalmol. 2020 Jun 13.

 

Parackova Z, Milota T, Vrabcova P, Smetanova J, Svaton M, Freiberger T, Kanderova V, Sediva A.

Novel XIAP mutation causing enhanced spontaneous apoptosis and disturbed NOD2 signalling in a patient with atypical adult-onset Crohn's disease

Cell Death Dis. 2020 Jun 8;11(6):430.

 

Machova Polakova K, Zizkova H, Zuna J, Motlova E, Hovorkova L, Gottschalk A, Glauche I, Koblihova J, Pecherkova P, Klamova H, Stastna Markova M, Srbova D, Benesova A, Polivkova V, Jurcek T, Zackova D, Mayer J, Ernst T, Mahon FX, Saussele S, Roeder I, Cross NCP, Hochhaus A.

Analysis of Chronic Myeloid Leukaemia During Deep Molecular Response by Genomic PCR: A Traffic Light Stratification Model With Impact on Treatment-Free Remission

Leukemia. 2020 May 29

 

Yang M, Safavi S, Woodward EL, Duployez N, Olsson-Arvidsson L, Ungerbäck J, Sigvardsson M, Zaliova M, Zuna J, Fioretos T, Johansson B, Nord KH, Paulsson K.

13q12.2 Deletions in Acute Lymphoblastic Leukemia Lead to Upregulation of FLT3 Through Enhancer Hijacking

Blood. 2020 May 8

 

Hermanova I, Zúñiga-García P, Caro-Maldonado A, Fernandez-Ruiz S, Salvador F, Martín-Martín N, Zabala-Letona A, Nuñez-Olle M, Torrano V, Camacho L, Lizcano JM, Talamillo A, Carreira S, Gurel B, Cortazar AR, Guiu M, López JI, Martinez-Romero A, Astobiza I, Valcarcel-Jimenez L, Lorente M, Arruabarrena-Aristorena A, Velasco G, Gomez-Muñoz A, Suárez-Cabrera C, Lodewijk I, Flores JM, Sutherland JD, Barrio R, de Bono JS, Paramio JM, Trka J, Graupera M, Gomis RR, Carracedo A.

Genetic Manipulation of LKB1 Elicits Lethal Metastatic Prostate Cancer

J Exp Med. 2020 Jun 1

 

Polaskova K, Merta T, Martincekova A, Zapletalova D, Kyr M, Mazanek P, Krenova Z, Mudry P, Jezova M, Tuma J, Skotakova J, Cervinkova I, Valik D, Zdrazilova-Dubska L, Noskova H, Pal K, Slaby O, Fabian P, Kozakova S, Neradil J, Veselska R, Kanderova V, Hrusak O, Freiberger T, Klement GL, Sterba J.

Comprehensive Molecular Profiling for Relapsed/Refractory Pediatric Burkitt Lymphomas-Retrospective Analysis of Three Real-Life Clinical Cases-Addressing Issues on Randomization and Customization at the Bedside.

Front Oncol. 2020 Feb 7

 

Kaneva K, Merkurjev D, Ostrow D, Ryutov A, Triska P, Stachelek K, Cobrinik D, Biegel JA, Gai X.

Detection of Mitochondrial DNA Variants at Low Level Heteroplasmy in Pediatric CNS and extra-CNS Solid Tumors With Three Different Enrichment Methods

Mitochondrion. Epub 2020 Jan 20

 

Kratochvíl M, Bednárek D, Sieger T, Fišer K, Vondrášek J.

ShinySOM: Graphical SOM-based analysis of single-cell cytometry data.

Bioinformatics. 2020 Feb 12

 

2019

Kalina T, Fišer K, Pérez-Andrés M, Kuzílková D, Cuenca M, Bartol SJW, Blanco E, Engel P, van Zelm MC.

CD Maps-Dynamic Profiling of CD1-CD100 Surface Expression on Human Leukocyte and Lymphocyte Subsets

Front Immunol. 2019 Oct 23

 

Glier H, Novakova M, Te Marvelde J, Bijkerk A, Morf D, Thurner D, Rejlova K, Lange S, Finke J, van der Sluijs-Gelling A, Sedek L, Flores-Montero J, Böttcher S, Fernandez P, Ritgen M, van Dongen JJM, Orfao A, van der Velden VHJ, Kalina T.

Comments on EuroFlow Standard Operating Procedures for Instrument Setup and Compensation for BD FACS Canto II, Navios and BD FACS Lyric Instruments

J Immunol Methods. 2019

 

Kalina T.

Reproducibility of Flow Cytometry Through Standardization: Opportunities and Challenges.

Cytometry A. 2019 Oct 8. doi: 10.1002/cyto.a.23901. [Epub ahead of print] Review.

 

Kalina T, Lundsten K, Engel P.

Relevance of Antibody Validation for Flow Cytometry.

Cytometry A. 2019 Oct 2. doi: 10.1002/cyto.a.23895. [Epub ahead of print] Review.

 

Formankova R, Kanderova V, Rackova M, Svaton M, Brdicka T, Riha P, Keslova P, Mejstrikova E, Zaliova M, Freiberger T, Grombirikova H, Zemanova Z, Vlkova M, Fencl F, Copova I, Bronsky J, Jabandziev P, Sedlacek P, Soukalova J, Zapletal O, Stary J, Trka J, Kalina T, Skvarova Kramarzova K, Hlavackova E, Litzman J and Fronkova E

Novel SAMD9 Mutation in a Patient With Immunodeficiency, Neutropenia, Impaired Anti-CMV Response, and Severe Gastrointestinal Involvement.

Front. Immunol., 18 September 2019

 

Bakardjieva-Mihaylova V, Skvarova Kramarzova K, Slamova M, Svaton M, Rejlova K, Zaliova M, Dobiasova A, Fiser K, Stuchly J, Grega M, Rosova B, Zachoval R, Klezl P, Eis V, Kindlova E, Buchler T, Trka J, Boublikova L.

Molecular Basis of Cisplatin Resistance in Testicular Germ Cell Tumors.

Cancers (Basel). 2019 Sep 6;11(9). pii: E1316

 

Vaskova M, Tichy M, Zamecnik J, Liby P, Kuzilkova D, Vicha A, Hrabeta J, Kalina T, Stary J, Hrusak O.

Cytometric analysis of cell suspension generated by cavitron ultrasonic surgical aspirator in pediatric brain tumors.

J Neurooncol. 2019 May;143(1):15-25.

 

Zaliova M, Stuchly J, Winkowska L, Musilova A, Fiser K, Slamova M, Starkova J, Vaskova M, Hrusak O, Sramkova L, Stary J, Zuna J, Trka J.

Genomic landscape of pediatric B-other acute lymphoblastic leukemia in a consecutive European cohort.

Haematologica. 2019 Jan 10. pii: haematol.2018.204974. doi: 10.3324/haematol.2018.204974. [Epub ahead of print]

 

Zaliova M, Potuckova E, Hovorkova L, Musilova A, Winkowska L, Fiser K, Stuchly J, Mejstrikova E, Starkova J, Zuna J, Stary J, Trka J.

ERG deletions in childhood acute lymphoblastic leukemia with DUX4 rearrangements are mostly polyclonal, prognostically relevant and their detection rate strongly depends on method's sensitivity.

Haematologica. 2019 Jan 10. pii: haematol.2018.204487. doi: 10.3324/haematol.2018.204487. [Epub ahead of print]

 

Hoffmann J, Fišer K, Liebetrau C, Staubach N, Kost D, Voss S, Heiden AZ, Dörr O, Lipps C, Nef HM, Möllmann H, Hamm CW, Keller T, Troidl C.

High-Content Immunophenotyping and Hierarchical Clustering Reveal Sources of Heterogeneity and New Surface Markers of Human Blood Monocyte Subsets

Thromb Haemost. Epub 2019 Dec 30.

 

Wentink MWJ, Kalina T, Perez-Andres M, Del Pino Molina L, IJspeert H, Kavelaars FG, Lankester AC, Lecrevisse Q, van Dongen JJM, Orfao A, van der Burg M.

Delineating Human B Cell Precursor Development With Genetically Identified PID Cases as a Model

Front Immunol. 2019 Nov 26

 

Parackova Z, Bloomfield M, Vrabcova P, Zentsova I, Klocperk A, Milota T, Svaton M, Casanova JL, Bustamante J, Fronkova E, Sediva A.

Mutual Alteration of NOD2-associated Blau Syndrome and IFNγR1 Deficiency

J Clin Immunol. 2019 Nov 23

 

Stranavova L, Pelak O, Svaton M, Hruba P, Fronkova E, Slavcev A, Osickova K, Maluskova J, Hubacek P, Fronek J, Reinke P, Volk HD, Kalina T, Viklicky O.

Heterologous Cytomegalovirus and Allo-Reactivity by Shared T Cell Receptor Repertoire in Kidney Transplantation

Front Immunol. 2019 Oct 31

 

Balounová J, Šplíchalová I, Dobešová M, Kolář M, Fišer K, Procházka J, Sedlacek R, Jurisicova A, Sung HK, Kořínek V, Alberich-Jorda M, Godin I, Filipp D.

Toll-like Receptor 2 Expression on C-Kit + Cells Tracks the Emergence of Embryonic Definitive Hematopoietic Progenitors

Nat Commun. 2019 Nov 15

 

Majer F, Kousal B, Dusek P, Piherova L, Reboun M, Mihalova R, Gurka J, Krebsova A, Vlaskova H, Dvorakova L, Krihova J, Liskova P, Kmoch S, Kalina T, Kubanek M, Sikora J.

Alu-mediated Xq24 Deletion Encompassing CUL4B, LAMP2, ATP1B4, TMEM255A, and ZBTB33 Genes Causes Danon Disease in a Female Patient

Am J Med Genet A. Epub 2019 Nov 15.

 

Cario G, Leoni V, Conter V, Attarbaschi A, Zaliova M, Sramkova L, Cazzaniga G, Fazio G, Sutton R, Elitzur S, Izraeli S, Lauten M, Locatelli F, Basso G, Buldini B, Bergmann AK, Lentes J, Steinemann D, Göhring G, Schlegelberger B, Haas OA, Schewe D, Buchmann S, Moericke A, White D, Revesz T, Stanulla M, Mann G, Bodmer N, Arad-Cohen N, Zuna J, Valsecchi MG, Zimmermann M, Schrappe M, Biondi A.

Relapses and Treatment-Related Events Contributed Equally to Poor Prognosis in Children With ABL-class Fusion Positive B-cell Acute Lymphoblastic Leukemia Treated According to AIEOP-BFM Protocols

Haematologica. 2019 Oct 10

 

Knecht H, Reigl T, Kotrová M, Appelt F, Stewart P, Bystry V, Krejci A, Grioni A, Pal K, Stranska K, Plevova K, Rijntjes J, Songia S, Svatoň M, Froňková E, Bartram J, Scheijen B, Herrmann D, García-Sanz R, Hancock J, Moppett J, van Dongen JJM, Cazzaniga G, Davi F, Groenen PJTA, Hummel M, Macintyre EA, Stamatopoulos K, Trka J, Langerak AW, Gonzalez D, Pott C, Brüggemann M, Darzentas N; EuroClonality-NGS Working Group.

Quality control and quantification in IG/TR next-generation sequencing marker identification: protocols and bioinformatic functionalities by EuroClonality-NGS.

Leukemia. 2019 Sep;33(9):2254-2265.

 

Brüggemann M, Kotrová M, Knecht H, Bartram J, Boudjogrha M, Bystry V, Fazio G, Froňková E, Giraud M, Grioni A, Hancock J, Herrmann D, Jiménez C, Krejci A, Moppett J, Reigl T, Salson M, Scheijen B, Schwarz M, Songia S, Svaton M, van Dongen JJM, Villarese P, Wakeman S, Wright G, Cazzaniga G, Davi F, García-Sanz R, Gonzalez D, Groenen PJTA, Hummel M, Macintyre EA, Stamatopoulos K, Pott C, Trka J, Darzentas N, Langerak AW; EuroClonality-NGS working group.

Standardized next-generation sequencing of immunoglobulin and T-cell receptor gene recombinations for MRD marker identification in acute lymphoblastic leukaemia; a EuroClonality-NGS validation study.

Leukemia. 2019 Sep;33(9):2241-2253.

 

Strakova V, Elblova L, Johnson MB, Dusatkova P, Obermannova B, Petruzelkova L, Kolouskova S, Snajderova M, Fronkova E, Svaton M, Lebl J, Hattersley AT, Sumnik Z, Pruhova S.

Screening of monogenic autoimmune diabetes among children with type 1 diabetes and multiple autoimmune diseases: is it worth doing?

J Pediatr Endocrinol Metab. 2019 Sep 4.

 

Prukova D, Andera L, Nahacka Z, Karolova J, Svaton M, Klanova M, Havranek O, Soukup J, Svobodova K, Zemanova Z, Tuskova D, Pokorna E, Helman K, Forsterova K, Pacheco-Blanco M, Vockova P, Berkova A, Fronkova E, Trneny M, Klener P.

Cotargeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal In Vivo in Relapsed Mantle Cell Lymphoma.

Clin Cancer Res. 2019 Jul 15;25(14):4455-4465.

 

van Dongen JJM, van der Burg M, Kalina T, Perez-Andres M, Mejstrikova E, Vlkova M, Lopez-Granados E, Wentink M, Kienzler AK, Philippé J, Sousa AE, van Zelm MC, Blanco E, Orfao A.

EuroFlow-Based Flowcytometric Diagnostic Screening and Classification of Primary Immunodeficiencies of the Lymphoid System.

Front Immunol. 2019 Jun 13;10:1271.

 

Flores-Montero J, Kalina T, Corral-Mateos A, Sanoja-Flores L, Pérez-Andrés M, Martin-Ayuso M, Sedek L, Rejlova K, Mayado A, Fernández P, van der Velden V, Bottcher S, van Dongen JJM, Orfao A.

Fluorochrome choices for multi-color flow cytometry.

J Immunol Methods. 2019 Jun 7. pii: S0022-1759(19)30132-2.

 

Rossner P, Vrbova K, Strapacova S, Rossnerova A, Ambroz A, Brzicova T, Libalova H, Javorkova E, Kulich P, Vecera Z, Mikuska P, Coufalik P, Krumal K, Capka L, Docekal B, Moravec P, Sery O, Misek I, Fictum P, Fiser K, Machala M, Topinka J.

Inhalation of ZnO Nanoparticles: Splice Junction Expression and Alternative Splicing in Mice.

Toxicol Sci. 2019 Mar 1;168(1):190-200.

 

Lin M, Nebral K, Gertzen CGW, Ganmore I, Haas OA, Bhatia S, Fischer U, Kuhlen M, Gohlke H, Izraeli S, Trka J, Hu J, Borkhardt A, Hauer J, Auer F.

JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility.

Leukemia. 2019 Apr 9

 

Meyer C, Lopes BA, Caye-Eude A, Cavé H, Arfeuille C, Cuccuini W, Sutton R, Venn NC, Oh SH, Tsaur G, Escherich G, Feuchtinger T, Kosasih HJ, Khaw SL, Ekert PG, Pombo-de-Oliveira MS, Bidet A, Djahanschiri B, Ebersberger I, Zaliova M, Zuna J, Zermanova Z, Juvonen V, Grümayer RP, Fazio G, Cazzaniga G, Larghero P, Emerenciano M, Marschalek R.

Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL-USP2 fusions.

Leukemia. 2019 Mar 21

 

Pfeifer H, Cazzaniga G, van der Velden VHJ, Cayuela JM, Schäfer B, Spinelli O, Akiki S, Avigad S, Bendit I, Borg K, Cavé H, Elia L, Reshmi SC, Gerrard G, Hayette S, Hermanson M, Juh A, Jurcek T, Chillón MC, Homburg C, Martinelli G, Kairisto V, Lange T, Lion T, Mueller MC, Pane F, Rai L, Damm-Welk C, Sacha T, Schnittger S, Touloumenidou T, Valerhaugen H, Vandenberghe P, Zuna J, Serve H, Herrmann E, Markovic S, Dongen JJMV, Ottmann OG.

Standardisation and consensus guidelines for minimal residual disease assessment in Philadelphia-positive acute lymphoblastic leukemia (Ph + ALL) by real-time quantitative reverse transcriptase PCR of e1a2 BCR-ABL1.

Leukemia. 2019 Mar 11.

 

van der Burg M, Kalina T, Perez-Andres M, Vlkova M, Lopez-Granados E, Blanco E, Bonroy C, Sousa AE, Kienzler AK, Wentink M, Mejstríková E, Šinkorova V, Stuchly J, van Zelm MC, Orfao A, van Dongen JJM.

The EuroFlow PID Orientation Tube for Flow Cytometric Diagnostic Screening of Primary Immunodeficiencies of the Lymphoid System.

Front Immunol. 2019 Mar 4

 

JM, Lorente F, Prieto C, Dávila I, Marcos M, Kalina T, Vlkova M, Chovancova Z, Cordeiro AI, Philippé J, Haerynck F, López-Granados E, Sousa AE, van der Burg M, van Dongen JJM, Orfao A; EuroFlow PID group.

Defects in memory B-cell and plasma cell subsets expressing different immunoglobulin-subclasses in patients with CVID and immunoglobulin subclass deficiencies.

J Allergy Clin Immunol. 2019 Feb 28.

 

Fišerová J, Maninová M, Sieger T, Uhlířová J, Šebestová L, Efenberková M, Čapek M, Fišer K, Hozák P.

Nuclear pore protein TPR associates with lamin B1 and affects nuclear lamina organization and nuclear pore distribution.

Cell Mol Life Sci. 2019 Feb 14

 

Poláková I, Pelák O, Thürner D, Pokrývková B, Tachezy R, Kalina T, Šmahel M.

Implementation of Mass Cytometry for Immunoprofiling of Patients with Solid Tumors.

J Immunol Res. 2019 Feb 11

 

Schinnerl D, Mejstrikova E, Schumich A, Zaliova M, Fortschegger K, Nebral K, Attarbaschi A, Fiser K, Kauer MO, Popitsch N, Haslinger S, Inthal A, Buldini B, Basso G, Bourquin JP, Gaipa G, Brüggemann M, Feuerstein T, Maurer-Granofszky M, Panzer-Grümayer R, Trka J, Mann G, Haas OA, Hrusak O, Dworzak MN, Strehl S.

CD371 cell surface expression: A unique feature of DUX4-rearranged acute lymphoblastic leukemia.

Haematologica. 2019 Jan 31

 

Kralickova P, Milota T, Litzman J, Malkusova I, Jilek D, Petanova J, Vydlakova J, Zimulova A, Fronkova E, Svaton M, Kanderova V, Bloomfield M, Parackova Z, Klocperk A, Haviger J, Kalina T, Sediva A.

CVID-Associated Tumors: Czech Nationwide Study Focused on Epidemiology, Immunology, and Genetic Background in a Cohort of Patients With CVID.

Front Immunol. 2019 Jan 22

 

Hamadeh L, Enshaei A, Schwab C, Alonso CN, Attarbaschi A, Barbany G, den Boer ML, Boer JM, Braun M, Dalla Pozza L, Elitzur S, Emerenciano M, Fechina L, Felice MS, Fronkova E, Haltrich I, Heyman MM, Horibe K, Imamura T, Jeison M, Kovács G, Kuiper RP, Mlynarski W, Nebral K, Ivanov Öfverholm I, Pastorczak A, Pieters R, Piko H, Pombo-de-Oliveira MS, Rubio P, Strehl S, Stary J, Sutton R, Trka J, Tsaur G, Venn N, Vora A, Yano M, Harrison CJ, Moorman AV; International BFM Study Group.

Validation of the United Kingdom copy-number alteration classifier in 3239 children with B-cell precursor ALL.

Blood Adv. 2019 Jan 22;3(2):148-157. doi: 10.1182/bloodadvances.2018025718.

 

Borna S, Drobek A, Kralova J, Glatzova D, Splichalova I, Fabisik M, Pokorna J, Skopcova T, Angelisova P, Kanderova V, Starkova J, Stanek P, Matveichuk OV, Pavliuchenko N, Kwiatkowska K, Protty MB, Tomlinson MG, Alberich-Jorda M, Korinek V, Brdicka T.

Transmembrane adaptor protein WBP1L regulates CXCR4 signalling and murine haematopoiesis.

J Cell Mol Med. 2019 Dec 17. doi: 10.1111/jcmm.14895. [Epub ahead of print]

 

2018

Hlozková K, Starková J.

Assessment of the Metabolic Profile of Primary Leukemia Cells.

J Vis Exp. 2018 Nov 21

 

Kanderova V, Grombirikova H, Zentsova I, Reblova K, Klocperk A, Fejtkova M, Bloomfield M, Ravcukova B, Kalina T, Freiberger T, Sediva A.

Lymphoproliferation, immunodeficiency and early-onset inflammatory bowel disease associated with a novel mutation in Caspase 8.

Haematologica. 2018 Oct 18. pii: haematol.2018.201673. doi: 10.3324/haematol.2018.201673.

 

Starý J, Zuna J, Zaliova M.

New biological and genetic classification and therapeutically relevant categories in childhood B-cell precursor acute lymphoblastic leukemia.

F1000Res. 2018 Sep 28;7. pii: F1000 Faculty Rev-1569. doi: 10.12688/f1000research.16074.1. eCollection 2018.

 

Kalina T, Brdickova N, Glier H, Fernandez P, Bitter M, Flores-Montero J, van Dongen J, Orfao A.

Frequent issues and lessons learned from EuroFlow QA.

J Immunol Methods. 2018 Sep 17. pii: S0022-1759(17)30140-0. doi: 10.1016/j.jim.2018.09.008.

 

Hrusak O, De Haas V, Stancikova J, Vakrmanova B, Janotova I, Mejstrikova E, Capek V, Trka J, Zaliova M, Luks A, Bleckmann K, Möricke A, Irving J, Konatkowska B, Alexander TB, Inaba H, Schmiegelow K, Stokley S, Zemanova Z, Moorman AV, Rossi JG, Felice MS, Dalla-Pozza L, Morales J, Dworzak M, Buldini B, Basso G, Campbell M, Cabrera ME, Marinov N, Elitzur S, Izraeli S, Luria D, Feuerstein T, Kolenova A, Svec P, Kreminska O, Rabin KR, Polychronopoulou S, da Costa E, Marquart HV, Kattamis A, Ratei R, Reinhardt D, Choi JK, Schrappe M, Stary J.

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia.

Blood. 2018 May 2. pii: blood-2017-12-821363. doi: 10.1182/blood-2017-12-821363.

 

Lukes J, Potuckova E, Sramkova L, Stary J, Starkova J, Trka J, Votava F, Zuna J, Zaliova M.

Two novel fusion genes, AIF1L-ETV6 and ABL1-AIF1L, result together with ETV6-ABL1 from a single chromosomal rearrangement in acute lymphoblastic leukemia with prenatal origin.

Genes Chromosomes Cancer. 2018 May 4. doi: 10.1002/gcc.6.

 

Starkova J, Hermanova I, Hlozkova K, Hararova A, Trka J.

Altered Metabolism of Leukemic Cells: New Therapeutic Opportunity.

Int Rev Cell Mol Biol. 2018;336:93-147. doi: 10.1016/bs.ircmb.2017.07.012. Epub 2017 Sep 18.

 

Majer F, Piherova L, Reboun M, Stara V, Pelak O, Norambuena P, Stranecky V, Krebsova A, Vlaskova H, Dvorakova L, Kmoch S, Kalina T, Kubanek M, Sikora J.

LAMP2 exon-copy number variations in Danon disease heterozygote female probands: Infrequent or underdetected?

Am J Med Genet A. 2018 Nov;176(11):2430-2434. doi: 10.1002/ajmg.a.40430. Epub 2018 Sep 8.

 

Kotrova M, Novakova M, Oberbeck S, Mayer P, Schrader A, Knecht H, Hrusak O, Herling M, Brüggemann M.

Next-generation amplicon TRB locus sequencing can overcome limitations of flow-cytometric Vβ expression analysis and confirms clonality in all T-cell prolymphocytic leukemia cases.

Cytometry A. 2018 Nov;93(11):1118-1124. doi: 10.1002/cyto.a.23604. Epub 2018 Nov 10.

 

Sikorski K, Mehta A, Inngjerdingen M, Thakor F, Kling S, Kalina T, Nyman TA, Stensland ME, Zhou W, de Souza GA, Holden L, Stuchly J, Templin M, Lund-Johansen F.

A high-throughput pipeline for validation of antibodies.

Nat Methods. 2018 Nov;15(11):909-912. doi: 10.1038/s41592-018-0179-8. Epub 2018 Oct 30.

 

Drabkin HA, Starkova J, Gemmill RM.

A triad of NRP2, DLX and p53 proteins in lung cancer metastasis.

Oncotarget. 2017 Oct 26

 

Valcarcel-Jimenez L, Macchia A, Martín-Martín N, Cortazar AR, Schaub-Clerigué A, Pujana-Vaquerizo M, Fernández-Ruiz S, Lacasa-Viscasillas I, Santos-Martin A, Loizaga-Iriarte A, Unda-Urzaiz M, Hermanova I, Astobiza I, Graupera M, Starkova J, Sutherland J, Barrio R, Aransay AM, Carracedo A, Torrano V.

Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer.

Cell Death Dis. 2018 Oct 11

 

Cortazar AR, Torrano V, Martín-Martín N, Caro-Maldonado A, Camacho L, Hermanova I, Guruceaga E, Lorenzo-Martín LF, Caloto R, Gomis RR, Apaolaza I, Quesada V, Trka J, Gomez-Muñoz A, Vicent S, Bustelo XR, Planes FJ, Aransay AM, Carracedo A.

CANCERTOOL: a visualization and representation interface to exploit cancer datasets.

Cancer Res. 2018 Sep 19. pii: canres.1669.2018. doi: 10.1158/0008-5472.CAN-18-1669.

 

Alexander TB, Gu Z, Iacobucci I, Dickerson K, Choi JK, Xu B, Payne-Turner D, Yoshihara H, Loh ML, Horan J, Buldini B, Basso G, Elitzur S, de Haas V, Zwaan CM, Yeoh A, Reinhardt D, Tomizawa D, Kiyokawa N, Lammens T, De Moerloose B, Catchpoole D, Hori H, Moorman A, Moore AS, Hrusak O, Meshinchi S, Orgel E, Devidas M, Borowitz M, Wood B, Heerema NA, Carrol A, Yang YL, Smith MA, Davidsen TM, Hermida LC, Gesuwan P, Marra MA, Ma Y, Mungall AJ, Moore RA, Jones SJM, Valentine M, Janke LJ, Rubnitz JE, Pui CH, Ding L, Liu Y, Zhang J, Nichols KE, Downing JR, Cao X, Shi L, Pounds S, Newman S, Pei D, Guidry Auvil JM, Gerhard DS, Hunger SP, Inaba H, Mullighan CG.

The genetic basis and cell of origin of mixed phenotype acute leukaemia.

Nature. 2018 Sep 12. doi: 10.1038/s41586-018-0436-0.

 

Klener P, Fronkova E, Kalinova M, Belada D, Forsterova K, Pytlik R, Blahovcova P, Simkovic M, Salek D, Mocikova H, Prochazka V, Janikova A, Vaskova M, Mejstrikova E, Kodet R, Trka J, Trneny M.

Potential loss of prognostic significance of minimal residual disease assessment after R-CHOP based induction in elderly patients with mantle cell lymphoma in the era of rituximab maintenance.

Hematol Oncol. 2018 Aug 20. doi: 10.1002/hon.2550.

 

Koblížek M, Lebedeva A, Fišer K.

flowIO: Flow cytometry standard conformance testing, editing, and export tool.

Cytometry A. 2018 Aug 15. doi: 10.1002/cyto.a.23563.

 

Bloomfield M, Kanderová V, Paračková Z, Vrabcová P, Svatoň M, Froňková E, Fejtková M, Zachová R, Rataj M, Zentsová I, Milota T, Klocperk A, Kalina T, Šedivá A.

Utility of Ruxolitinib in a Child with Chronic Mucocutaneous Candidiasis Caused by a Novel STAT1 Gain-of-Function Mutation.

J Clin Immunol. 2018 Jun 22. doi: 10.1007/s10875-018-0519-6.

 

Yeoh AE, Li Z, Dong D, Lu Y, Jiang N, Trka J, Tan AM, Lin HP, Quah TC, Ariffin H, Wong L.

Effective Response Metric: a novel tool to predict relapse in childhood acute lymphoblastic leukaemia using time-series gene expression profiling.

Br J Haematol. 2018 Jun;181(5):653-663. doi: 10.1111/bjh.15252.

 

Schwab C, Gabrysch A, Olbrich P, Patiño V, Warnatz K, Wolff D, Hoshino A, Kobayashi M, Imai K, Takagi M, Dybedal I, Haddock JA, Sansom DM, Lucena JM, Seidl M, Schmitt-Graeff A, Reiser V, Emmerich F, Frede N, Bulashevska A, Salzer U, Schubert D, Hayakawa S, Okada S, Kanariou M, Kucuk ZY, Chapdelaine H, Petruzelkova L, Sumnik Z, Sediva A, Slatter M, Arkwright PD, Cant A, Lorenz HM, Giese T, Lougaris V, Plebani A, Price C, Sullivan KE, Moutschen M, Litzman J, Freiberger T, van de Veerdonk FL, Recher M, Albert MH, Hauck F, Seneviratne S, Pachlopnik Schmid J, Kolios A, Unglik G, Klemann C, Speckmann C, Ehl S, Leichtner A, Blumberg R, Franke A, Snapper S, Zeissig S, Cunningham-Rundles C, Giulino-Roth L, Elemento O, Dückers G, Niehues T, Fronkova E, Kanderová V, Platt CD, Chou J, Chatila TA, Geha R, McDermott E, Bunn S, Kurzai M, Schulz A, Alsina L, Casals F, Deyà-Martinez A, Hambleton S, Kanegane H, Taskén K, Neth O, Grimbacher B.

Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects.

J Allergy Clin Immunol. 2018 May 4. pii: S0091-6749(18)30630-4. doi: 10.1016/j.jaci.2018.02.055.

 

Blanco E, Pérez-Andrés M, Arriba-Méndez S, Contreras-Sanfeliciano T, Criado I, Pelak O, Serra-Caetano A, Romero A, Puig N, Remesal A, Torres Canizales J, López-Granados E, Kalina T, Sousa AE, van Zelm M, van der Burg M, van Dongen JJM, Orfao A; EuroFlow PID group.

Age-associated distribution of normal B-cell and plasma cell subsets in peripheral blood.

J Allergy Clin Immunol. 2018 Mar 2. pii: S0091-6749(18)30305-1. doi: 10.1016/j.jaci.2018.02.017.

 

Sędek Ł, Theunissen P, da Costa ES, van der Sluijs-Gelling A, Mejstrikova E, Gaipa G, Sonsala A, Twardoch M, Oliveira E, Novakova M, Buracchi C, van Dongen JJM, Orfao A, van der Velden VHJ, Szczepański T; EuroFlow Consortium.

Differential expression of CD73, CD86 and CD304 in normal vs. leukemic B-cell precursors and their utility as stable minimal residual disease markers in childhood B-cell precursor acute lymphoblastic leukemia.

J Immunol Methods. 2018 Mar 9. pii: S0022-1759(17)30126-6. doi: 10.1016/j.jim.2018.03.005.

 

Hnízda A, Fábry M, Moriyama T, Pachl P, Kugler M, Brinsa V, Ascher DB, Carroll WL, Novák P, Žaliová M, Trka J, Řezáčová P, Yang JJ, Veverka V.

Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.

Leukemia. 2018 Feb 25. doi: 10.1038/s41375-018-0073-5.

 

Cazzaniga G, De Lorenzo P, Alten J, Röttgers S, Hancock J, Saha V, Castor A, Madsen HO, Gandemer V, Cavé H, Leoni V, Köhler R, Ferrari GM, Bleckmann K, Pieters R, van der Velden V, Stary J, Zuna J, Escherich G, Stadt UZ, Aricò M, Conter V, Schrappe M, Valsecchi MG, Biondi A.

Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies.

Haematologica. 2018 Jan;103(1):107-115. doi: 10.3324/haematol.2017.176917. Epub 2017 Oct 27.

 

2017

Mejstříková E, Hrusak O, Borowitz MJ, Whitlock JA, Brethon B, Trippett TM, Zugmaier G, Gore L, von Stackelberg A, Locatelli F.

CD19-negative relapse of pediatric B-cell precursor acute lymphoblastic leukemia following blinatumomab treatment.

Blood Cancer J. 2017 Dec 20;7(12):659. doi: 10.1038/s41408-017-0023-x.

 

Rejlová K, Musilová A, Škvárová Kramarzová K, Žaliová M, Fišer K, Alberich-Jorda M, Trka J, Starková J.

LOW HOX gene expression in PML-RARα-POSITIVE leukemia results from suppressed histone demethylation.

Epigenetics. 2017 Dec 11:1-25. doi: 10.1080/15592294.2017.1413517.

 

Nováková M, Glier H, Brdičková N, Vlková M, Santos AH, Lima M, Roussel M, Flores-Montero J, Szczepanski T, Böttcher S, van der Velden VHJ, Fernandez P, Mejstříková E, Burgos L, Paiva B, van Dongen JJM, Orfao A, Kalina T.

How to make usage of the standardized EuroFlow 8-color protocols possible for instruments of different manufacturers.

J Immunol Methods. 2017 Nov 20. pii: S0022-1759(17)30139-4. doi: 10.1016/j.jim.2017.11.007.

 

Zaliova M, Kotrova M, Bresolin S, Stuchly J, Stary J, Hrusak O, Te Kronnie G, Trka J, Zuna J, Vaskova M.

ETV6/RUNX1-like acute lymphoblastic leukemia: A novel B-cell precursor leukemia subtype associated with the CD27/CD44 immunophenotype.

Genes Chromosomes Cancer. 2017 Aug;56(8):608-616. doi: 10.1002/gcc.22464. Epub 2017 May 5.

 

Zimmermannova O, Doktorova E, Stuchly J, Kanderova V, Kuzilkova D, Strnad H, Starkova J, Alberich-Jorda M, Falkenburg JHF, Trka J, Petrak J, Zuna J, Zaliova M.

An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia.

Oncogene. 2017 Jun 26. doi: 10.1038/onc.2017.210.

 

Skvarova Kramarzova K, Osborn MJ, Webber BR, DeFeo AP, McElroy AN, Kim CJ, Tolar J.

CRISPR/Cas9-Mediated Correction of the FANCD1 Gene in Primary Patient Cells.

Int J Mol Sci. 2017 Jun 14;18(6). pii: E1269. doi: 10.3390/ijms18061269.

 

Zimmermannova O, Zaliova M, Moorman AV, Al-Shehhi H, Fronkova E, Zemanova Z, Kalina T, Vora A, Stary J, Trka J, Hrusak O, Zuna J.

Acute lymphoblastic leukemia with aleukemic prodrome: preleukemic dynamics and possible mechanisms of immunosurveillance.

Haematologica. 2017 Jun;102(6):e225-e228. doi: 10.3324/haematol.2016.161380. Epub 2017 Mar 2.

 

Kotrova M, Trka J, Kneba M, Brüggemann M.

Is Next-Generation Sequencing the way to go for Residual Disease Monitoring in Acute Lymphoblastic Leukemia?

Mol Diagn Ther. 2017 Apr 27. doi: 10.1007/s40291-017-0277-9.

 

Hovorkova L, Zaliova M, Venn NC, Bleckmann K, Trkova M, Potuckova E, Vaskova M, Linhartova J, Machova Polakova K, Fronkova E, Muskovic W, Giles JE, Shaw PJ, Cario G, Sutton R, Stary J, Trka J, Zuna J.

Monitoring of childhood ALL using BCR-ABL1 genomic breakpoints identifies a subgroup with CML-like biology.

Blood. 2017 May 18;129(20):2771-2781. doi: 10.1182/blood-2016-11-749978. Epub 2017 Mar 22.

 

Lhermitte L, Mejstrikova E, van der Sluijs-Gelling AJ, Grigore GE, Sedek L, Bras AE, Gaipa G, Sobral da Costa E, Novakova M, Sonneveld E, Buracchi C, de Sá Bacelar T, Te Marvelde JG, Trinquand A, Asnafi V, Szczepanski T, Matarraz S, Lopez A, Vidriales B, Bulsa J, Hrusak O, Kalina T, Lecrevisse Q, Martin Ayuso M, Brüggemann M, Verde J, Fernandez P, Burgos L, Paiva B, Pedreira CE, van Dongen JJM, Orfao A, van der Velden VHJ.

Automated database-guided expert-supervised orientation for immunophenotypic diagnosis and classification of acute leukemia.

Leukemia. 2017 Nov 1. doi: 10.1038/leu.2017.313.

 

Cazzaniga G, De Lorenzo P, Alten J, Röttgers S, Hancock J, Saha V, Castor A, Madsen HO, Gandemer V, Cavé H, Leoni V, Köhler R, Ferrari GM, Bleckmann K, Pieters R, Van der Velden V, Stary J, Zuna J, Escheric G, Zur Stadt U, Aricò M, Conter V, Schrappe M, Valsecchi MG, Biondi A.

Predictive value of MRD in Ph+ ALL treated with imatinib in the EsPhALL study, based on IG/TR and BCR/ABL1 methodologies.

Haematologica. 2017 Oct 27. pii: haematol.2017.176917. doi: 10.3324/haematol.2017.176917.

 

Parackova Z, Klocperk A, Rataj M, Kayserova J, Zentsova I, Sumnik Z, Kolouskova S, Sklenarova J, Pruhova S, Obermannova B, Petruzelkova L, Lebl J, Kalina T, Sediva A.

Alteration of B cell subsets and the receptor for B cell activating factor (BAFF) in paediatric patients with type 1 diabetes.

Immunol Lett. 2017 Apr 14. pii: S0165-2478(17)30104-9. doi: 10.1016/j.imlet.2017.04.009.

 

Theunissen PMJ, Sedek L, De Haas V, Szczepanski T, Van Der Sluijs A, Mejstrikova E, Nováková M, Kalina T, Lecrevisse Q, Orfao A, Lankester AC, van Dongen JJM, Van Der Velden VHJ; EuroFlow Consortium.

Detailed immunophenotyping of B-cell precursors in regenerating bone marrow of acute lymphoblastic leukaemia patients: implications for minimal residual disease detection.

Br J Haematol. 2017 Apr 17. doi: 10.1111/bjh.14682.

 

Böttcher S, van der Velden VHJ, Villamor N, Ritgen M, Flores-Montero J, Murua Escobar H, Kalina T, Brüggemann M, Grigore G, Martin-Ayuso M, Lecrevisse Q, Pedreira CE, van Dongen JJM, Orfao A.

Lot-to-lot stability of antibody reagents for flow cytometry.

J Immunol Methods. 2017 Mar 30. pii: S0022-1759(17)30075-3. doi: 10.1016/j.jim.2017.03.018.

 

van der Velden VH, Flores-Montero J, Perez-Andres M, Martin-Ayuso M, Crespo O, Blanco E, Kalina T, Philippé J, Bonroy C, de Bie M, Te Marvelde J, Teodosio C, Corral Mateos A, Kanderová V, van der Burg M, Van Hoof D, van Dongen JJ, Orfao A.

Optimization and testing of dried antibody tube: The EuroFlow LST and PIDOT tubes as examples.

J Immunol Methods. 2017 Mar 22. pii: S0022-1759(17)30095-9. doi: 10.1016/j.jim.2017.03.011.

 

Sediva H, Dusatkova P, Kanderova V, Obermannova B, Kayserova J, Sramkova L, Zemkova D, Elblova L, Svaton M, Zachova R, Kolouskova S, Fronkova E, Sumnik Z, Sediva A, Lebl J, Pruhova S.

Short Stature in a Boy with Multiple Early-Onset Autoimmune Conditions due to a STAT3 Activating Mutation: Could Intracellular Growth Hormone Signalling Be Compromised?

Horm Res Paediatr. 2017 Mar 2. doi: 10.1159/000456544.

 

Dworzak MN, Buldini B, Gaipa G, Ratei R, Hrusak O, Luria D, Rosenthal E, Bourquin JP, Sartor M, Schumich A, Karawajew L, Mejstrikova E, Maglia O, Mann G, Ludwig WD, Biondi A, Schrappe M, Basso G; International-BFM-FLOW-network.

AIEOP-BFM consensus guidelines 2016 for flow cytometric immunophenotyping of Pediatric acute lymphoblastic leukemia.

Cytometry B Clin Cytom. 2017 Feb 10. doi: 10.1002/cyto.b.21518.

 

jablovskaja P, Kardosova M, Danek P, Angelisova P, Benoukraf T, Wurm AA, Kalina T, Sian S, Balastik M, Delwel R, Brdicka T, Tenen DG, Behre G, Fiore F, Malissen B, Horejsi V, Alberich-Jorda M.

EVI2B is a C/EBPα target gene required for granulocytic differentiation and functionality of hematopoietic progenitors.

Cell Death Differ. 2017 Feb 10.doi: 10.1038/cdd.2017.6.

 

Křížová L, Kuchař M, Petroková H, Osička R, Hlavničková M, Pelák O, Černý J, Kalina T, Malý P.

p19-targeted ABD-derived protein variants inhibit IL-23 binding and exert suppressive control over IL-23-stimulated expansion of primary human IL-17+ T-cells.

Autoimmunity. 2017 Jan 19:1-12. doi: 10.1080/08916934.2016.1272598.

 

2016

Zaliova M, Moorman AV, Cazzaniga G, Stanulla M, Harvey RC, Roberts KG, Heatley SL, Loh ML, Konopleva M, Chen IM, Zimmermannova O, Schwab C, Smith O, Mozziconacci MJ, Chabannon C, Kim M, Frederik Falkenburg JH, Norton A, Marshall K, Haas OA, Starkova J, Stuchly J, Hunger SP, White D, Mullighan CG, Willman CL, Stary J, Trka J, Zuna J.

Characterization of leukemias with ETV6-ABL1 fusion.

Haematologica. 2016 Sep;101(9):1082-93. doi: 10.3324/haematol.2016.144345. Epub 2016 May 26

 

Kotrova M, Musilova A, Stuchly J, Fiser K, Starkova J, Mejstrikova E, Stary J, Zuna J, Hrusak O, Trka J, Zaliova M.

Distinct bilineal leukemia immunophenotypes are not genetically determined.

Blood. 2016 Sep 13. pii: blood-2016-07-725861.

 

Zaliova M, Hovorkova L, Vaskova M, Hrusak O, Stary J, Zuna J.

Slower early response to treatment and distinct expression profile of childhood high hyperdiploid acute lymphoblastic leukaemia with DNA index < 1.16.

Genes Chromosomes Cancer. 2016 Sep;55(9):727-37. doi: 10.1002/gcc.22374

 

Potuckova E, Zuna J, Hovorkova L, Starkova J, Stary J, Trka J, Zaliova M.

Intragenic ERG Deletions Do Not Explain the Biology of ERG-Related Acute Lymphoblastic Leukemia.

PLoS One. 2016 Aug 5;11(8):e0160385. doi: 10.1371/journal.pone.0160385. eCollection 2016.

 

Pelák O, Kužílková D, Thürner D, Kiene ML, Stanar K, Stuchlý J, Vášková M, Starý J, Hrušák O, Stadler H, Kalina T.

Lymphocyte enrichment using CD81-targeted immunoaffinity matrix.

Cytometry A. 2016 Aug 4. doi: 10.1002/cyto.a.22918. [Epub ahead of print]

 

Klener P, Fronkova E, Berkova A, Jaksa R, Lhotska H, Forsterova K, Soukup J, Kulvait V, Vargova J, Fiser K, Prukova D, Alam M, Calvin Lenyeletse Maswabi B, Michalova K, Zemanova Z, Jancuskova T, Pekova S, Trneny M.

Mantle cell lymphoma-variant Richter syndrome: Detailed molecular-cytogenetic and backtracking analysis reveals slow evolution of a pre-MCL clone in parallel with CLL over several years.

Int J Cancer. 2016 Jul 12. doi: 10.1002/ijc.30263. [Epub ahead of print]

 

Zuna J, Moericke A, Arens M, Koehler R, Panzer-Grümayer R, Bartram CR, Fischer S, Fronkova E, Zaliova M, Schrauder A, Stanulla M, Zimmermann M, Trka J, Stary J, Attarbaschi A, Mann G, Schrappe M, Cario G.

Implications of delayed bone marrow aspirations at the end of treatment induction for risk stratification and outcome in children with acute lymphoblastic leukaemia.

Br J Haematol. 2016 Feb 23. doi: 10.1111/bjh.13989.

 

Michaela Novakova, Marketa Zaliova, Martina Sukova, Marcin Wlodarski, Ales Janda, Eva Fronkova, Vit Campr, Katerina Lejhancova, Ondrej Zapletal, DagmarPospisilova, Zdenka Cerna,Tomas Kuhn, Peter Svec, Vendula Pelkova, Zuzana Zemanova, Gitte Kerndrup, Marry van den Heuvel-ibrink, Vincent vanderVelden, Charlotte Niemeyer, Tomas Kalina, Jan Trka, Jan Stary,  Ondrej Hrusak, Ester Mejstrikova.

Loss of B cells and their precursors is the most constant feature of GATA-2 deficiency in childhood myelodysplastic syndrome.

Haematologica March 2016 : Doi:10.3324/haematol.2015.137711

 

Boublikova L, Bakardjieva-Mihaylova V, Skvarova Kramarzova K, Kuzilkova D, Dobiasova A, Fiser K, Stuchly J, Kotrova M, Buchler T, Dusek P, Grega M, Rosova B, Vernerova Z, Klezl P, Pesl M, Zachoval R, Krolupper M, Kubecova M, Stahalova V, Abrahamova J, Babjuk M, Kodet R, Trka J.

Wilms tumor gene 1 (WT1), TP53, RAS/BRAF and KIT aberrations in testicular germ cell tumors.

Cancer Lett. 2016 Jul 1;376(2):367-76. doi: 10.1016/j.canlet.2016.04.016. Epub 2016 Apr 13.

 

Kanderova V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, Hrusak O, Lund-Johansen F, Kalina T.

High-resolution antibody array analysis of childhood acute leukemia cells.

Mol Cell Proteomics. 2016 Jan 19. pii: mcp.M115.054593. [Epub ahead of print]

 

Theunissen P, Mejstrikova E, Sedek L, van der Sluijs-Gelling AJ, Gaipa G, Bartels M, Sobral da Costa E, Kotrova M, Novakova M, Sonneveld E, Buracchi C, Bonaccorso P, Oliviera E, Te Marvelde JG, Szczepanski T, Lhermitte L, Hrusak O, Lecrevisse Q, Grigore GE, Fronkova E, Trka J, Brüggemann M, Orfao A, van Dongen JJ, van der Velden VH.

Standardized flow cytometry for highly sensitive MRD measurements in B-cell acute lymphoblastic leukemia.

Blood. 2016 Nov 30. pii: blood-2016-07-726307.

 

de Rooij JD, van den Heuvel-Eibrink MM, van de Rijdt NK, Verboon LJ, de Haas V, Trka J, Baruchel A, Reinhardt D, Pieters R, Fornerod M, Zwaan CM.

PHF6 mutations in paediatric acute myeloid leukaemia.

Br J Haematol. 2016 Dec;175(5):967-971. doi: 10.1111/bjh.13891.

 

Pytlík R, Rentsch C, Soukup T, Novotný L, Rentsch B, Kanderová V, Rychtrmocová H, Kalmárová M, Stehlík D, Trněný M, Slanař O.

Efficacy and safety of human mesenchymal stromal cells in healing of critical-size bone defects in immunodeficient rats.

Physiol Res. 2016 Oct 26.

 

Verboon LJ, Obulkasim A, de Rooij JD, Katsman-Kuipers JE, Sonneveld E, Baruchel A, Trka J, Reinhardt D, Pieters R, Cloos J, Kaspers GJ, Klusmann JH, Zwaan CM, Fornerod M, van den Heuvel-Eibrink MM.

MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia.

Oncotarget. 2016 Jun 24. doi: 10.18632/oncotarget.10270

 

Lund-Johansen F, de la Rosa Carrillo D, Mehta A, Sikorski K, Inngjerdingen M, Kalina T, Røysland K, Antonio de Souza G, Bradbury AR, Lecrevisse Q, Stuchly J.

MetaMass, a tool for meta-analysis of subcellular proteomics data.

Nat Methods. 2016 Aug 29. doi: 10.1038/nmeth.3967

 

de Rooij JD, Masetti R, van den Heuvel-Eibrink MM, Cayuela JM, Trka J, Reinhardt D, Rasche M, Sonneveld E, Alonzo TA, Fornerod M, Zimmermann M, Pigazzi M, Pieters R, Meshinchi S, Zwaan CM, Locatelli F.

Recurrent genetic abnormalities can be used for risk-group stratification in pediatric AMKL: results of a retrospective intergroup study.

Blood. 2016 Apr 25. pii: blood-2016-01-695551

 

2015

Pelák O, Stuchlý J, Król L, Hubáček P, Keslová P, Sedláček P, Formánková R, Starý J, Hrušák O, Kalina T.

Appearance of CMV specific T-cells predicts fast resolution of viremia post hematopoietic Stem cell transplantation.

Cytometry B Clin Cytom. 2015 Dec 8. doi: 10.1002/cyto.b.21348. [Epub ahead of print]

 

Polgárová K, Vášková M, Froňková E, Slámová L, Kalina T, Mejstříková E, Dobiášová A, Hrušák O.

Quantitative expression of regulatory and differentiation-related genes in the key steps of human hematopoiesis: The LeukoStage Database.

Differentiation. 2015 Dec 7. pii: S0301-4681(15)00072-9. doi: 10.1016/j.diff.2015.11.003. [Epub ahead of print]

 

Kotrova M, Muzikova K, Mejstrikova E, Novakova M, Bakardjieva-Mihaylova V, Fiser K, Stuchly J, Giraud M, Salson M, Pott C, Brüggemann M, Füllgrabe M, Stary J, Trka J, Fronkova E.

The predictive strength of next-generation sequencing MRD detection for relapse compared with current methods in childhood ALL.

Blood. 2015 Aug 20;126(8):1045-7. doi: 10.1182/blood-2015-07-655159.

 

Heřmanová I, Arruabarrena-Aristorena A, Vališ K, Nůsková H, Jorda MA, Fišer K, Fernández-Ruiz S, Kavan D, Pecinová A, Niso-Santano M, Žaliová M, Novák P, Houštěk J, Mráček T, Kroemer G, Carracedo A, Trka J, Starková J.

Pharmacological inhibition of fatty acid oxidation synergistically enhances the effect of L-asparaginase in childhood ALL cells.

Leukemia. 2015 Aug 4. doi: 10.1038/leu.2015.213. [Epub ahead of print]

 

Fišer K, Slámová L, Bourquin JP, Trka J, Starý J, Hrušák O, Mejstříková E.

Reprogramming of B cell acute lymphoblastic leukemia cells: Do we need to shoot a moving target?

Proc Natl Acad Sci U S A. 2015 Jun 11. pii: 201508680. [Epub ahead of print]

 

Dytrych P., Krol P., Kotrova M., Kuzilkova D., Hubacek P., Krol L., Katra R., Hrusak O, Kabelka Z., Dolezalova P., Kalina T., Fronkova E.

Polyclonal, newly derived T cells with low expression of inhibitory molecule PD-1 in tonsils define the phenotype of lymphocytes in children with Periodic Fever, Aphtous Stomatitis, Pharyngitis and Adenitis (PFAPA) syndrome.

Mol Immunol. 2015 May;65(1):139-47. doi: 10.1016/j.molimm.2015.01.004.

 

Svojgr K, Sumerauer D, Puchmajerova A, Vicha A, Hrusak O, Michalova K, Malis J, Smisek P, Kyncl M, Novotna D, Machackova E, Jencik J, Pycha K, Vaculik M, Kodet R, Stary J.

Fanconi anemia with biallelic FANCD1/BRCA2 mutations - Case report of a family with three affected children.

Eur J Med Genet. 2015 Dec 2. pii: S1769-7212(15)30051-3. doi: 10.1016/j.ejmg.2015.11.013. [Epub ahead of print]

 

Liskova P, Evans CJ, Davidson AE, Zaliova M, Dudakova L, Trkova M, Stranecky V, Carnt N, Plagnol V, Vincent AL, Tuft SJ, Hardcastle AJ.

Heterozygous deletions at the ZEB1 locus verify haploinsufficiency as the mechanism of disease for posterior polymorphous corneal dystrophy type 3.

Eur J Hum Genet. 2015 Oct 28. doi: 10.1038/ejhg.2015.232. [Epub ahead of print]

 

Szotkowski T, Jarošová M, Zimmermannová O, Meyer C, Marschalek R, Zuna J, Hubáček J, Indrák K.

Long-term remission of therapy-related acute myeloid leukemia with a new t(11;18)(q23;q21.2) translocation and KMT2A-ME2 (MLL-ME2) fusion gene.

Cancer Genet. 2015 Dec;208(12):610-4. doi: 10.1016/j.cancergen.2015.09.004. Epub 2015 Sep 15.

 

Avigad S, Verly IR, Lebel A, Kordi O, Shichrur K, Ohali A, Hameiri-Grossman M, Kaspers GJ, Cloos J, Fronkova E, Trka J, Luria D, Kodman Y, Mirsky H, Gaash D, Jeison M, Avrahami G, Elitzur S, Gilad G, Stark B, Yaniv I.

miR expression profiling at diagnosis predicts relapse in pediatric precursor B-cell acute lymphoblastic leukemia.

Genes Chromosomes Cancer. 2015 Dec 19. doi: 10.1002/gcc.22334.

 

Klocperk A, Mejstříková E, Kayserová J, Kalina T, Šedivá A.

Low marginal zone-like B lymphocytes and natural antibodies characterize skewed B-lymphocyte subpopulations in del22q11 DiGeorge patients.

Clin Immunol. 2015 Sep 2;161(2):144-149. doi: 10.1016/j.clim.2015.08.013.

 

Linhartova J, Hovorkova L, Soverini S, Benesova A, Jaruskova M, Klamova H, Zuna J, Machova Polakova K.

Characterization of 46 patient-specific BCR-ABL1 fusions and detection of SNPs upstream and downstream the breakpoints in chronic myeloid leukemia using next generation sequencing.

Mol Cancer. 2015 Apr 18;14:89. doi: 10.1186/s12943-015-0363-8.

 

Vlkova M, Ticha O, Nechvatalova J, Kalina T, Litzman J, Mauri C, Blair PA.

Regulatory B cells in CVID patients fail to suppress multifunctional IFN-γ+TNF-α+CD4+ T cells differentiation.

Clin Immunol. 2015 Jul 29;160(2):292-300. doi: 10.1016/j.clim.2015.06.013. [Epub ahead of print]

 

Fischer U, Forster M, Rinaldi A, Risch T, Sungalee S, Warnatz HJ, Bornhauser B, Gombert M, Kratsch C, Stütz AM, Sultan M, Tchinda J, Worth CL, Amstislavskiy V, Badarinarayan N, Baruchel A, Bartram T, Basso G, Canpolat C, Cario G, Cavé H, Dakaj D, Delorenzi M, Dobay MP, Eckert C, Ellinghaus E, Eugster S, Frismantas V, Ginzel S, Haas OA, Heidenreich O, Hemmrich-Stanisak G, Hezaveh K, Höll JI, Hornhardt S, Husemann P, Kachroo P, Kratz CP, Kronnie GT, Marovca B, Niggli F, McHardy AC, Moorman AV, Panzer-Grümayer R, Petersen BS, Raeder B, Ralser M, Rosenstiel P, Schäfer D, Schrappe M, Schreiber S, Schütte M, Stade B, Thiele R, Weid NV, Vora A, Zaliova M, Zhang L, Zichner T, Zimmermann M, Lehrach H, Borkhardt A, Bourquin JP, Franke A, Korbel JO, Stanulla M, Yaspo ML.

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.

Nat Genet. 2015 Jul 27. doi: 10.1038/ng.3362. [Epub ahead of print]

 

Boer JM, van der Veer A, Rizopoulos D, Fiocco M, Sonneveld E, de Groot-Kruseman HA, Kuiper RP, Hoogerbrugge P, Horstmann M, Zaliova M, Palmi C, Trka J, Fronkova E, Emerenciano M, do Socorro Pombo-de-Oliveira M, Mlynarski W, Szczepanski T, Nebral K, Attarbaschi A, Venn N, Sutton R, Schwab CJ, Enshaei A, Vora A, Stanulla M, Schrappe M, Cazzaniga G, Conter V, Zimmermann M, Moorman AV, Pieters R, den Boer ML.

Prognostic value of rare IKZF1 deletion in childhood B-cell precursor acute lymphoblastic leukemia: an international collaborative study.

Leukemia. 2015 Jul 23. doi: 10.1038/leu.2015.199. [Epub ahead of print]

 

Svobodova T, Mejstrikova E, Salzer U, Sukova M, Hubacek P, Matej R, Vasakova M, Hornofova L, Dvorakova M, Fronkova E, Votava F, Freiberger T, Pohunek P, Stary J, Janda A.

Diffuse parenchymal lung disease as first clinical manifestation of GATA-2 deficiency in childhood.

BMC Pulm Med. 2015 Feb 10;15:8. doi: 10.1186/s12890-015-0006-2.

 

Bugarin C, Sarno J, Palmi C, Savino AM, Te Kronnie G, Dworzak M, Shumich A, Buldini B, Maglia O, Sala S, Bronzini I, Bourquin JP, Mejstrikova E, Hrusak O, Luria D, Basso G, Izraeli S, Biondi A, Cazzaniga G, Gaipa G; I-BFM study group.

Fine tuning of surface CRLF2 expression and its associated signaling profile in childhood B-cell precursor acute lymphoblastic leukemia.

Haematologica. 2015 Jun;100(6):e229-32. doi: 10.3324/haematol.2014.114447. Epub 2015 Apr 10.

 

Felgentreff K, Lee YN, Frugoni F, Du L, van der Burg M, Giliani S, Tezcan I, Reisli I, Mejstrikova E, Villartay JP, Sleckman BP, Manis J, Notarangelo LD.

Functional analysis of naturally occurring DCLRE1C mutations and correlation with the clinical phenotype of ARTEMIS deficiency.

J Allergy Clin Immunol. 2015 Apr 25. pii: S0091-6749(15)00345-0. doi: 10.1016/j.jaci.2015.03.005.

 

Zdráhalová K, Štěrba J, Domanský J, Blažek B, Ptoszková H, Mihál V, Novák Z, Hak J, Procházková D, Černá Z, Timr P, Jabali Y, Sedláček P, Smíšek P, Zemanová Z, Jarošová M, Houdková A, Mejstříková E, Hrušák O, Zuna J, Janotová I, Trka J, Starý J.

[The prospects for children with acute lymphoblastic leukemia of being cured has increased in the Czech Republic in the 21st century to 90% - outcome of the ALL-IC BFM 2002 trial].

Cas Lek Cesk. 2015;154(2):79-89. Czech.

 

Basak A, Hancarova M, Ulirsch JC, Balci TB, Trkova M, Pelisek M, Vlckova M, Muzikova K, Cermak J, Trka J, Dyment DA, Orkin SH, Daly MJ, Sedlacek Z, Sankaran VG.

BCL11A deletions result in fetal hemoglobin persistence and neurodevelopmental alterations.

J Clin Invest. 2015 Jun 1;125(6):2363-8. doi: 10.1172/JCI81163. Epub 2015 May 4.

 

Šálek C, Folber F, Froňková E, Procházka B, Marinov I, Cetkovský P, Mayer J, Doubek M.

Early mrd response as a prognostic factor in adult patients with acute lymphoblastic leukemia.

Eur J Haematol. 2015 May 21. doi: 10.1111/ejh.12587. [Epub ahead of print]

 

Karawajew L, Dworzak M, Ratei R, Rhein P, Gaipa G, Buldini B, Basso G, Hrusak O, Ludwig WD, Henze G, Seeger K, von Stackelberg A, Mejstrikova E, Eckert C.

Minimal residual disease analysis by eight-color flow cytometry in relapsed childhood acute lymphoblastic leukemia.

Haematologica. 2015 May 22. pii: haematol.2014.116707. [Epub ahead of print]

 

de Rooij JD, Beuling E, van den Heuvel-Eibrink MM, Obulkasim A, Baruchel A, Trka J, Reinhardt D, Sonneveld E, Gibson BE, Pieters R, Zimmermann M, Zwaan CM, Fornerod M.

Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia.

Haematologica. 2015 Jun 11. pii: haematol.2015.124321. [Epub ahead of print]. 2015 Mar 17. doi:10.1038/leu.2015.78

 

Sikora J, Majer F, Kalina T.

LAMP2 flow cytometry in peripheral white blood cells is an established method that facilitates identification of heterozygous Danon disease female patients and mosaic mutation carriers.

J Cardiol. 2015 Jan 27. pii: S0914-5087(15)00006-4. doi: 10.1016/j.jjcc.2014.12.014. [Epub ahead of print]

 

2014

Kalina T, Flores-Montero J, Lecrevisse Q, Pedreira CE, van der Velden VH, Novakova M, Mejstrikova E, Hrusak O, Böttcher S, Karsch D, Sędek L, Trinquand A, Boeckx N, Caetano J, Asnafi V, Lucio P, Lima M, Helena Santos A, Bonaccorso P, van der Sluijs-Gelling AJ, Langerak AW, Martin-Ayuso M, Szczepański T, van Dongen JJ, Orfao A.

Quality assessment program for EuroFlow protocols: Summary results of four-year (2010-2013) quality assurance rounds.

Cytometry A. 2014 Oct 23. doi: 10.1002/cyto.a.22581.

 

Hrušák O, Basso G, Ratei R, Gaipa G, Luria D, Mejstříková E, Karawajew L, Buldini B, Rozenthal E, Bourquin JP, Kalina T, Sartor M, Dworzak MN; AIEOP-BFM Flow Network.

Flow diagnostics essential code: a simple and brief format for the summary of leukemia phenotyping.

Cytometry B Clin Cytom. 2014 Jul;86(4):288-91.

 

Stary J, Zimmermann M, Campbell M, Castillo L, Dibar E, Donska S, Gonzalez A, Izraeli S, Janic D, Jazbec J, Konja J, Kaiserova E, Kowalczyk J, Kovacs G, Li CK, Magyarosy E, Popa A, Stark B, Jabali Y, Trka J, Hrusak O, Riehm H, Masera G, Schrappe M.

Intensive Chemotherapy for Childhood Acute Lymphoblastic Leukemia: Results of the Randomized Intercontinental Trial ALL IC-BFM 2002.

J Clin Oncol. 2014 Jan 20;32(3):174-84. doi: 10.1200/JCO.2013.48.6522. Epub 2013 Dec 16.

 

Kováč M, Vášková M, Petráčková D, Pelková V, Mejstříková E, Kalina T, Zaliová M, Weiser J, Starý J, Hrušák O.

Cytokines, growth, and environment factors in bone marrow plasma of acute lymphoblastic leukemia pediatric patients.

Eur Cytokine Netw. 2014 Mar 1;25(1):8-13. doi: 10.1684/ecn.2014.0348.

 

Froňková E, Klocperk A, Svatoň M, Nováková M, Kotrová M, Kayserová J, Kalina T, Keslová P, Votava F, Vinohradská H, Freiberger T, Mejstříková E, Trka J, Sedivá A.

The TREC/KREC Assay for the Diagnosis and Monitoring of Patients with DiGeorge Syndrome.

PLoS One. 2014 Dec 8;9(12):e114514. doi: 10.1371/journal.pone.0114514. eCollection 2014.

 

Kramarzova K, Fiser K, Mejstrikova E, Rejlova K, Zaliova M, Fornerod M, Drabkin HA, van den Heuvel-Eibrink MM, Stary J, Trka J, Starkova J.

Homeobox gene expression in acute myeloid leukemia is linked to typical underlying molecular aberrations.

J Hematol Oncol. 2014 Dec 24;7(1):1. [Epub ahead of print]

 

Kalinova M, Fronkova E, Klener P, Forsterova K, Lokvenc M, Mejstrikova E, Belada D, Mocikova H, Trneny M, Kodet R, Trka J.

The use of formalin-fixed, paraffin-embedded lymph node samples for the detection of minimal residual disease in mantle cell lymphoma.

Br J Haematol. 2014 Oct 14. doi: 10.1111/bjh.13182.

 

Hoffmann J, Shmeleva E, Boag SE, Fiser K, Bagnall A, Murali S, Dimmick I, Pircher H, Martin-Ruiz C, Egred M, Keavney B, von Zglinicki T, Das R, Todryk S, Spyridopoulos I.

Myocardial Ischemia and Reperfusion Leads to Transient CD8 Immune Deficiency and Accelerated Immunosenescence in CMV-Seropositive Patients.

Circ Res. 2014 Nov 10. pii: CIRCRESAHA.114.304393. [Epub ahead of print]

 

Klocperk A, Grecová J, Šišmová K, Kayserová J, Froňková E, Šedivá A.

Helios expression in T-regulatory cells in patients with di George Syndrome.

J Clin Immunol. 2014 Oct;34(7):864-70. doi: 10.1007/s10875-014-0071-y. Epub 2014 Jul 10.

 

Lizcova L, Zemanova Z, Lhotska H, Zuna J, Hovorkova L, Mejstrikova E, Malinova E, Rabasova J, Raska I, Sramkova L, Stary J, Michalova K.

An unusual case of high hyperdiploid childhood ALL with cryptic BCR/ABL1 rearrangement.

Mol Cytogenet. 2014 Oct 24;7(1):72. doi: 10.1186/s13039-014-0072-9. eCollection 2014.

 

Fucikova J, Moserova I, Truxova I, Hermanova I, Vancurova I, Partlova S, Fialova A, Sojka L, Cartron PF, Houska M, Rob L, Bartunkova J, Spisek R.

High hydrostatic pressure induces immunogenic cell death in human tumor cells.

Int J Cancer. 2014 Feb 5. doi: 10.1002/ijc.28766.

 

Papaemmanuil E, Rapado I, Li Y, Potter NE, Wedge DC, Tubio J, Alexandrov LB, Van Loo P, Cooke SL, Marshall J, Martincorena I, Hinton J, Gundem G, van Delft FW, Nik-Zainal S, Jones DR, Ramakrishna M, Titley I, Stebbings L, Leroy C, Menzies A, Gamble J, Robinson B, Mudie L, Raine K, O'Meara S, Teague JW, Butler AP, Cazzaniga G, Biondi A, Zuna J, Kempski H, Muschen M, Ford AM, Stratton MR, Greaves M, Campbell PJ.

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.

Nat Genet. 2014 Feb;46(2):116-25. doi: 10.1038/ng.2874. Epub 2014 Jan 12.

 

Ijspeert H, Driessen GJ, Moorhouse MJ, Hartwig NG, Wolska-Kusnierz B, Kalwak K, Pituch-Noworolska A, Kondratenko I, van Montfrans JM, Mejstrikova E, Lankester AC, Langerak AW, van Gent DC, Stubbs AP, van Dongen JJ, van der Burg M.

Similar recombination-activating gene (RAG) mutations result in similar immunobiological effects but in different clinical phenotypes.

J Allergy Clin Immunol. 2014 Jan 10. pii: S0091-6749(13)01848-4. doi: 10.1016/j.jaci.2013.11.028.

 

Yang JJ, Park TS, Lee ST, Seo JY, Oh SH, Cho EH, Strehl S, Mühlegger N, Dworzak MN, Zuna J, Pospisilova D, Meyer C, Marschalek R, Kim HJ, Kim SH.

Molecular characterization and clinical impact of t(11;15)(q23;q14-15) MLL-CASC5 rearrangement.

Haematologica. 2014 Jan;99(1):e11-3. doi: 10.3324/haematol.2013.095638.

 

2013

Ondřej Hrušák, Giuseppe Basso, Richard Ratei, Giuseppe Gaipa, Drorit Luria, Ester Mejstříková, Leonid Karawajew, Barbara Buldini, Eti Rozenthal, Jean Pierre Bourquin, Tomáš Kalina, Mary Sartor and Michael N. Dworzak, on behalf of the AIEOP-BFM Flow Network.

Flow diagnostics essential (FDE) code: A simple and brief format for the summary of leukemia phenotyping

Cytometry B 2013 doi: 10.1002/cytob.21144

 

Jan Stuchly, Tomas Kalina

Analyses of Large Flow Cytometry Datasets

Cytometry A 2013 doi: 10.1002/cyto.a.22431

 

Slamova L, Starkova J, Fronkova E, Zaliova MK, Reznickova LR, van Delft FW, Vodickova E, Volejnikova J, Zemanova Z, Polgarova K, Cario G, Figueroa M, Kalina T, Fiser K, Bourquin JP, Bornhauser B, Dworzak M, Zuna J, Trka J, Stary J, Hrusak O, Mejstrikova E.

CD2-positive B-cell precursor acute lymphoblastic leukemia with an early switch to the monocytic lineage.

Leukemia 2013 Nov 25. 

 

Boublikova L, Buchler T, Stary J, Abrahamova J, Trka J.

Molecular biology of testicular germ cell tumors: Unique features awaiting clinical application.

Crit Rev Oncol Hematol. 2013

 

Zaliova M, Zimmermanova O, Dörge P, Eckert C, Möricke A, Zimmermann M, Stuchly J, Teigler-Schlegel A, Meissner B, Koehler R, Bartram CR, Karawajew L,Rhein P, Zuna J, Schrappe M, Cario G, Stanulla M.

ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia.

Leukemia. 2013 Sep 27

 

Froňková E.

[Next-generation sequencing].

Cesk Patol. 2013 Jun

 

van der Veer A, Zaliova M, Mottadelli F, De Lorenzo P, Te Kronnie G, Harrison CJ, Cavé H, Trka J, Saha V, Schrappe M, Pieters R, Biondi A, Valsecchi MG, Stanulla M, den Boer ML, Cazzaniga G.

IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL.

Blood. 2013 Dec 23.

 

Milan Kuchař, Lucie Vaňková, Hana Petroková, Jiří Černý, Radim Osička, Ondřej Pelák, Hana Šípová, Bohdan Schneider, Jiří Homola, Peter Šebo, Tomáš Kalina and Petr Malý.

Human interleukin-23 receptor antagonists derived from an albumin-binding domain scaffold inhibit IL-23-dependent ex vivo expansion of IL-17-producing T-cells

Proteins: Structure, Function, and Bioinformatics 2013 doi: 10.1002/prot.24472

 

Meissner B, Bartram T, Eckert C, Trka J, Panzer-Grümayer R, Hermanova I, Ellinghaus E, Franke A, Möricke A, Schrauder A, Teigler-Schlegel A, Dörge P, von Stackelberg A, Basso G, Bartram CR, Kirschner-Schwabe R, Bornhäuser B, Bourquin JP, Cazzaniga G, Hauer J, Attarbaschi A, Izraeli S, Zaliova M, Cario G, Zimmermann M, Avigad S, Sokalska-Duhme M, Metzler M, Schrappe M, Koehler R, Kronnie GT, Stanulla M.

Frequent and sex-biased deletion of SLX4IP by illegitimate V(D)J-mediated recombination in childhood acute lymphoblastic leukemia.

Hum Mol Genet. 2013 Sep 17.

 

Cheng SH, Lau KM, Li CK, Chan NP, Ip RK, Cheng CK, Lee V, Shing MM, Leung AW, Ha SY, Cheuk DK, Lee AC, Li CH, Luk CW, Ling SC, Hrusak O, Mejstrikova E, Leung Y, Ng MH.

Minimal residual disease-based risk stratification in chinese childhood acute lymphoblastic leukemia by flow cytometry and plasma DNA quantitative polymerase chain reaction.

PLoS One. 2013 Jul 25

 

Rensing-Ehl A, Janda A, Lorenz MR, Gladstone BP, Fuchs I, Abinun M, Albert M, Butler K, Cant AJ, Cseh AM, Ebinger M, Goldacker S, Hambleton S, Hebart H, Houet L, Kentouche K, Kühnle I, Lehmberg K, Mejstrikova E, Niemeyer C, Minkov M, Neth O, Dückers G, Owens S, Roesler J, Schilling FH, Schuster V, Seidel MG, Smisek P, Sukova M, Svec P, Wiesel T, Gathmann B, Schwarz K, Vach W, Ehl S, Speckmann C.

Sequential decisions on FAS sequencing guided by biomarkersin patients with lymphoproliferation and autoimmune cytopenia.

Haematologica. 2013 Jul 19

 

Majer F, Pelak O, Kalina T, Vlaskova H, Dvorakova L, Honzik T, Palecek T, Kuchynka P, Masek M, Zeman J, Elleder M, Sikora J.

Mosaic tissue distribution of the tandem duplication of LAMP2 exons 4 and 5 demonstrates the limits of Danon disease cellular and molecular diagnostics.

J Inherit Metab Dis. 2013 May 29

 

Meyer C, Hofmann J, Burmeister T, Gröger D, Park TS, Emerenciano M, Pombo de Oliveira M, Renneville A, Villarese P, Macintyre E, Cavé H, Clappier E, Mass-Malo K, Zuna J, Trka J, De Braekeleer E, De Braekeleer M, Oh SH, Tsaur G, Fechina L, van der Velden VH, van Dongen JJ, Delabesse E, Binato R, Silva ML, Kustanovich A, Aleinikova O, Harris MH, Lund-Aho T, Juvonen V, Heidenreich O, Vormoor J, Choi WW, Jarosova M, Kolenova A, Bueno C, Menendez P, Wehner S, Eckert C, Talmant P, Tondeur S, Lippert E, Launay E, Henry C, Ballerini P, Lapillone H, Callanan MB, Cayuela JM, Herbaux C, Cazzaniga G, Kakadiya PM, Bohlander S, Ahlmann M, Choi JR, Gameiro P, Lee DS, Krauter J, Cornillet-Lefebvre P, Te Kronnie G, Schäfer BW, Kubetzko S, Alonso CN, Zur Stadt U, Sutton R, Venn NC, Izraeli S, Trakhtenbrot L, Madsen HO, Archer P, Hancock J, Cerveira N, Teixeira MR, Lo Nigro L, Möricke A, Stanulla M, Schrappe M, Sedék L, Szczepański T, Zwaan CM, Coenen EA, van den Heuvel-Eibrink MM, Strehl S, Dworzak M, Panzer-Grümayer R, Dingermann T, Klingebiel T, Marschalek R.

The MLL recombinome of acute leukemias in 2013.

Leukemia. 2013 Apr 30.

 

Mirkowska P, Hofmann A, Sedek L, Slamova L, Mejstrikova E, Szczepanski T, Schmitz M, Cario G, Stanulla M, Schrappe M, van der Velden VH, Bornhauser BC, Wollscheid B, Bourquin JP.

Leukemia surfaceome analysis reveals new disease-associated features.

Blood. 2013 May 6

 

de Rooij JD, Hollink IH, Arentsen-Peters ST, van Galen JF, Beverloo HB, Baruchel A, Trka J, Reinhardt D, Sonneveld E, Zimmermann M, Alonzo TA, Pieters R, Meshinchi S, van den Heuvel-Eibrink MM, Zwaan CM.

NUP98/JARID1A is a novel recurrent abnormality in pediatric acute megakaryoblastic leukemia with a distinct HOX-gene expression pattern.

Leukemia. 2013 Mar 27

 

Aalbers AM, Calado RT, Young NS, Zwaan CM, Wu C, Kajigaya S, Coenen EA, Baruchel A, Geleijns K, de Haas V, Kaspers GJ, Kuijpers TW, Reinhardt D, Trka J, Zimmermann M, Pieters R, van der Velden VH, van den Heuvel-Eibrink MM.

Telomere length and telomerase complex mutations in pediatric acute myeloid leukemia.

Leukemia. 2013 Feb 21.

 

Bessho F, Takayama N, Fronkova E, Zuna J.

Reappearance of acute lymphoblastic leukemia 34 years after initial diagnosis: a case report and study of the origin of the reappeared blasts.

Int J Hematol. 2013 Feb 19.

 

2012

Kramarzova K, Boublikova L, Stary J, Trka J.

Evaluation of WT1 expression in bone marrow vs peripheral blood samples of children with acute myeloid leukemia-impact on minimal residual disease detection.

Leukemia. 2012 Oct 10.

 

Volejnikova J, Mejstrikova E, Dörge P, Meissner B, Zimmermannova O, Svojgr K, Stanulla M, Cario G, Schrappe M, Stary J, Hrusak O, Trka J, Fronkova E.

Ikaros (IKZF1) alterations and minimal residual disease at day 15 assessed by flow cytometry predict prognosis of childhood BCR/ABL-negative acute lymphoblastic leukemia.

Pediatr Blood Cancer. 2012 Sep 19

 

Mejstríková E, Janda A, Hrusák O, Bucková H, Vlcková M, Hancárová M, Freiberger T, Ravcuková B, Vesely K, Fajkusová L, Kopecková L, Sumerauer D, Kabícková E, Sedivá A, Stary J, Sedlácek Z.

Skin lesions in a boy with X-linked lymphoproliferative disorder: comparison of 5 SH2D1A deletion cases.

Pediatrics. 2012 Feb;129(2):e523-8. Epub 2012 Jan 23.

 

Kalina T, Flores-Montero J, van der Velden VH, Martin-Ayuso M, Böttcher S, Ritgen M, Almeida J, Lhermitte L, Asnafi V, Mendonça A, de Tute R, Cullen M, Sedek L, Vidriales MB, Pérez JJ, Te Marvelde JG, Mejstrikova E, Hrusak O, Szczepański T, van Dongen JJ, Orfao A.

EuroFlow standardization of flow cytometer instrument settings and immunophenotyping protocols.

Leukemia. 2012 Sep;26(9):1986-2010. doi: 10.1038/leu.2012.122.

 

Hermanova I, Zaliova MK, Trka J, Starkova J.

Low expression of asparagine synthetase in lymphoid blasts precludes its role in sensitivity to L-asparaginase.

Exp Hematol. 2012 Apr 25. [Epub ahead of print]

 

Kramarzova K, Stuchly J, Willasch A, Gruhn B, Schwarz J, Cermak J, Machova-Polakova K, Fuchs O, Stary J, Trka J, Boublikova L.

Real-time PCR quantification of major Wilms' tumor gene 1 (WT1) isoforms in acute myeloid leukemia, their characteristic expression patterns and possible functional consequences.

Leukemia, 2012 Mar 20. [Epub ahead of print] 

 

Stuchly, J., Kanderova, V., Fiser, K., Cerna, D., Holm, A., Wu, W., Hrusak, O., Lund-Johansen, F., Kalina, T.

An automated analysis of highly complex flow cytometry-based proteomic data

Cytometry A (2012), Feb; 81(2), 120-129

 

Svojgr, K., Kalina, T., Kanderova, V., Skopcova, T., Brdicka, T., Zuna, J.

The adaptor protein NTAL enhances proximal signaling and potentiates corticosteroid-induced apoptosis in T-ALL

Exp Hematol, 2012 Jan 20. [Epub ahead of print]

 

Zapotocky, M., Mejstrikova, E., Smetana, K., Stary, J., Trka, J., & Starkova, J.

Valproic acid triggers differentiation and apoptosis in AML1/ETO-positive leukemic cells specifically

Cancer Lett, 2012 Jan 17. [Epub ahead of print]

 

Fiser, K., Sieger, T., Schumich, A., Wood, B., Irving, J., Mejstrikova, E., & Dworzak, M. N.

Detection and monitoring of normal and leukemic cell populations with hierarchical clustering of flow cytometry data

Cytometry A (2012), Jan;81(1):25-34

 

Hoffmann J, Fiser K, Weaver J, Dimmick I, Loeher M, Pircher H, Martin-Ruiz C, Veerasamy M, Keavney B, von Zglinicki T, Spyridopoulos I.

High-throughput 13-parameter immunophenotyping identifies shifts in the circulating T-cell compartment following reperfusion in patients with acute myocardial infarction.

PLoS One. 2012;7(10)

 

Aalbers AM, Calado RT, Young NS, Zwaan CM, Kajigaya S, Baruchel A, Geleijns K, de Haas V, Kaspers GJ, Reinhardt D, Trka J, Kuijpers TW, Pieters R, van der Velden VH, van den Heuvel-Eibrink MM.

Absence of SBDS mutations in sporadic paediatric acute myeloid leukaemia.

Br J Haematol. 2012 Nov 28

 

Lutz C, Woll PS, Hall G, Castor A, Dreau H, Cazzaniga G, Zuna J, Jensen C, Clark SA, Biondi A, Mitchell C, Ferry H, Schuh A, Buckle V, Jacobsen SE, Enver T.

Quiescent leukaemic cells account for minimal residual disease in childhood lymphoblastic leukaemia.

Leukemia. 2012 Oct 22. doi: 10.1038/leu.2012.306. [Epub ahead of print]

 

Creutzig U, van den Heuvel-Eibrink MM, Gibson B, Dworzak MN, Adachi S, de Bont E, Harbott J, Hasle H, Johnston D, Kinoshita A, Lehrnbecher T, Leverger G,Mejstrikova E, Meshinchi S, Pession A, Raimondi SC, Sung L, Stary J, Zwaan CM, Kaspers GJ, Reinhardt D; on behalf of the AML Committee of the International BFM Study Group.

Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel.

Blood. 2012 Oct 18;120(16):3187-3205. Epub 2012 Aug 9.

 

Dekking EH, van der Velden VH, Varro R, Wai H, Böttcher S, Kneba M, Sonneveld E, Koning A, Boeckx N, Van Poecke N, Lucio P, Mendonça A, Sedek L, Szczepański T, Kalina T, Kanderová V, Hoogeveen P, Flores-Montero J, Chillón MC, Orfao A, Almeida J, Evans P, Cullen M, Noordijk AL, Vermeulen PM, de Man MT, Dixon EP, Comans-Bitter WM, van Dongen JJ.

Flow cytometric immunobead assay for fast and easy detection of PML-RARA fusion proteins for the diagnosis of acute promyelocytic leukemia.

Leukemia. 2012 Sep;26(9):1976-85. doi: 10.1038/leu.2012.125. Epub 2012 May 8.

 

Inthal A, Zeitlhofer P, Zeginigg M, Morak M, Grausenburger R, Fronkova E, Fahrner B, Mann G, Haas OA, Panzer-Grümayer R.

CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia.

Leukemia. 2012 Aug;26(8):1797-803. doi: 10.1038/leu.2012.60. Epub 2012 Mar 5.

 

Luesink M, Hollink IH, van der Velden VH, Knops RH, Boezeman JB, de Haas V, Trka J, Baruchel A, Reinhardt D, van der Reijden BA, van den Heuvel-Eibrink MM, Zwaan CM, Jansen JH.

High GATA2 expression is a poor prognostic marker in pediatric acute myeloid leukemia.

Blood. 2012 Jul 11. [Epub ahead of print]

 

Pagel J, Beutel K, Lehmberg K, Koch F, Maul-Pavicic A, Rohlfs AK, Al-Jefri A, Beier R, Bomme Ousager L, Ehlert K, Gross-Wieltsch U, Jorch N, Kremens B,Pekrun A, Sparber-Sauer M, Mejstrikova E, Wawer A, Ehl S, zur Stadt U, Janka G.

Distinct mutations in STXBP2 are associated with variable clinical presentations in patients with familial hemophagocytic lymphohistiocytosis type 5 (FHL5).

Blood. 2012 Jun 21;119(25):6016-24. Epub 2012 Mar 26.

 

van Dongen JJ, Lhermitte L, Böttcher S, Almeida J, van der Velden VH, Flores-Montero J, Rawstron A, Asnafi V, Lécrevisse Q, Lucio P, Mejstrikova E, Szczepañski T, Kalina T, de Tute R, Brüggemann M, Sedek L, Cullen M, Langerak AW, Mendonça A, Macintyre E, Martin-Ayuso M, Hrusak O, Vidriales MB, Orfao

EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes.

Leukemia, 2012 May 3.[Epub ahead of print]

 

Inthal A, Zeitlhofer P, Zeginigg M, Morak M, Grausenburger R, Fronkova E, Fahrner B, Mann G, Haas OA, Panzer-Grümayer R.

CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia.

Leukemia, 2012 Mar 5.[Epub ahead of print]

 

Majer, F., Vlaskova, H., Krol, L., Kalina, T., Kubanek, M., Stolnaya, L., Dvorakova, L., Elleder, M., & Sikora, J. 

Danon disease: A focus on processing of the novel LAMP2 mutation and comments on the beneficial use of peripheral white blood cells in the diagnosis of LAMP2 deficiency

Gene, 2012 May 1;498(2):183-95

 

Bodor, C., Renneville, A., Smith, M., Charazac, A., Iqbal, S., Etancelin, P., Cavenagh, J., Barnett, M. J., Kramarzova, K., Krishnan, B., Matolcsy, A., Preudhomme, C., Fitzgibbon, J., & Owen, C.

Germ-line GATA2 p.THR354MET mutation in familial myelodysplastic syndrome with acquired monosomy 7 and ASXL1 mutation demonstrating rapid onset and poor survival

Haematologica, 2012 Jan 22. [Epub ahead of print]

 

2011

Volejnikova, J., Mejstrikova, E., Valova, T., Reznickova, L., Hodonska, L., Mihal, V., Sterba, J., Jabali, Y., Prochazkova, D., Blazek, B., Hak, J., Cerna, Z., Hrusak, O., Stary, J., Trka, J., & Fronkova, E.

Minimal residual disease in peripheral blood at day 15 identifies subgroup of childhood B-cell precursor acute lymphoblastic leukemia with superior prognosis

Haematologica (2011), Dec;96(12):1815-21

 

Starkova, J., Gadgil, S., Qiu, Y. H., Zhang, N., Hermanova, I., Kornblau, S. M., & Drabkin, H. A.

Up-regulation of homeodomain genes, DLX1 and DLX2, by FLT3 signaling

Haematologica (2011), 96(6), 820-828

 

Zuna, J., Madzo, J., Krejci, O., Zemanova, Z., Kalinova, M., Muzikova, K., Zapotocky, M., Starkova, J., Hrusak, O., Horak, J., & Trka, J.

ETV6/RUNX1 (TEL/AML1) is a frequent prenatal first hit in childhood leukemia

Blood (2011), 117(1), 368-369; author reply 370-361

Vaskova, M., Kovac, M., Volna, P., Angelisova, P., Mejstrikova, E., Zuna, J., Brdicka, T., & Hrusak, O.

High expression of cytoskeletal protein drebrin in TEL/AML1(pos) B-cell precursor acute lymphoblastic leukemia identified by a novel monoclonal antibody

Leuk Res (2011), 35(8), 1111-1113

 

Zaliova, M., Meyer, C., Cario, G., Vaskova, M., Marschalek, R., Stary, J., Zuna, J., & Trka, J.

TEL/AML1-positive patients lacking TEL exon 5 resemble canonical TEL/AML1 cases

Pediatr Blood Cancer (2011), 56(2), 217-225

 

Zaliova, M., Madzo, J., Cario, G., & Trka, J.

Revealing the role of TEL/AML1 for leukemic cell survival by RNAi-mediated silencing

Leukemia (2011), Feb;25(2):313-20

 

Krol, L., Stuchly, J., Hubacek, P., Keslova, P., Sedlacek, P., Stary, J., Hrusak, O., & Kalina, T.

Signature profiles of CMV-specific T-cells in patients with CMV reactivation after hematopoietic SCT

Bone Marrow Transplant (2011), 46(8), 1089-1098

 

Ellinghaus, E., Stanulla, M., Richter, G., Ellinghaus, D., Te Kronnie, G., Cario, G., Cazzaniga, G., Horstmann, M., Panzer Grumayer, R., Cave, H., Trka, J., Cinek, O., Teigler-Schlegel, A., Elsharawy, A., Hasler, R., Nebel, A., Meissner, B., Bartram, T., Lescai, F., Franceschi, C., Giordan, M., Nurnberg, P., Heinzow, B., Zimmermann, M., Schreiber, S., Schrappe, M., & Franke, A.

Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia

Leukemia (2011),

 

Slaastad, H., Wu, W., Goullart, L., Kanderova, V., Tjonnfjord, G., Stuchly, J., Kalina, T., Holm, A., & Lund-Johansen, F.

Multiplexed immuno-precipitation with 1725 commercially available antibodies to cellular proteins

Proteomics (2011), 11(23), 4578-4582

 

Hollink, I. H., Feng, Q., Danen-van Oorschot, A. A., Arentsen-Peters, S. T., Verboon, L. J., Zhang, P., de Haas, V., Reinhardt, D., Creutzig, U., Trka, J., Pieters, R., van den Heuvel-Eibrink, M. M., Wang, J., & Zwaan, C. M.

Low frequency of DNMT3A mutations in pediatric AML, and the identification of the OCI-AML3 cell line as an in vitro model

Leukemia (2011),

 

Danen-van Oorschot, A. A., Kuipers, J. E., Arentsen-Peters, S., Schotte, D., de Haas, V., Trka, J., Baruchel, A., Reinhardt, D., Pieters, R., Michel Zwaan, C., & van den Heuvel-Eibrink, M. M.

Differentially expressed miRNAs in cytogenetic and molecular subtypes of pediatric acute myeloid leukemia

Pediatr Blood Cancer (2011),

 

Hollink, I. H., van den Heuvel-Eibrink, M. M., Arentsen-Peters, S. T., Pratcorona, M., Abbas, S., Kuipers, J. E., van Galen, J. F., Beverloo, H. B., Sonneveld, E., Kaspers, G. J., Trka, J., Baruchel, A., Zimmermann, M., Creutzig, U., Reinhardt, D., Pieters, R., Valk, P. J., & Zwaan, C. M.

NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern

Blood (2011), 118(13), 3645-3656

 

Stepanek, O., Kalina, T., Draber, P., Skopcova, T., Svojgr, K., Angelisova, P., Horejsi, V., Weiss, A., & Brdicka, T.

Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148

J Biol Chem (2011), 286(25), 22101-22112

 

van Delft, F. W., Horsley, S., Colman, S., Anderson, K., Bateman, C., Kempski, H., Zuna, J., Eckert, C., Saha, V., Kearney, L., Ford, A., & Greaves, M.

Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia

Blood (2011), 117(23), 6247-6254

 

Hollink, I. H., van den Heuvel-Eibrink, M. M., Arentsen-Peters, S. T., Zimmermann, M., Peeters, J. K., Valk, P. J., Balgobind, B. V., Sonneveld, E., Kaspers, G. J., de Bont, E. S., Trka, J., Baruchel, A., Creutzig, U., Pieters, R., Reinhardt, D., & Zwaan, C. M.

Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia

Haematologica (2011), 96(3), 384-392

 

Pachlopnik Schmid, J., Canioni, D., Moshous, D., Touzot, F., Mahlaoui, N., Hauck, F., Kanegane, H., Lopez-Granados, E., Mejstrikova, E., Pellier, I., Galicier, L., Galambrun, C., Barlogis, V., Bordigoni, P., Fourmaintraux, A., Hamidou, M., Dabadie, A., Le Deist, F., Haerynck, F., Ouachee-Chardin, M., Rohrlich, P., Stephan, J. L., Lenoir, C., Rigaud, S., Lambert, N., Milili, M., Schiff, C., Chapel, H., Picard, C., de Saint Basile, G., Blanche, S., Fischer, A., & Latour, S.

Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency)

Blood (2011), 117(5), 1522-1529

 

Balgobind, B. V., Van den Heuvel-Eibrink, M. M., De Menezes, R. X., Reinhardt, D., Hollink, I. H., Arentsen-Peters, S. T., van Wering, E. R., Kaspers, G. J., Cloos, J., de Bont, E. S., Cayuela, J. M., Baruchel, A., Meyer, C., Marschalek, R., Trka, J., Stary, J., Beverloo, H. B., Pieters, R., Zwaan, C. M., & den Boer, M. L.

Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia

Haematologica (2011), 96(2), 221-230

 

Sediva, A., Polouckova, A., Podrazil, M., Fronkova, E., & Kalina, T.

Characterization of the B-cell compartment in a patient with Schnitzler syndrome

Scand J Rheumatol (2011), 40(2), 158-160

 

2010

Vlkova, M., Fronkova, E., Kanderova, V., Janda, A., Ruzickova, S., Litzman, J., Sediva, A., & Kalina, T. Characterization of Lymphocyte Subsets in Patients with

Characterization of lymphocyte subsets in patients with common variable immunodeficiency reveals subsets of naive human B cells marked by CD24 expression

J Immunol (2010), 185(11), 6431-6438

 

Starkova, J., Zamostna, B., Mejstrikova, E., Krejci, R., Drabkin, H. A., & Trka, J.

HOX gene expression in phenotypic and genotypic subgroups and low HOXA gene expression as an adverse prognostic factor in pediatric ALL

Pediatr Blood Cancer (2010), 55(6), 1072-1082

 

Zuna, J., Zaliova, M., Muzikova, K., Meyer, C., Lizcova, L., Zemanova, Z., Brezinova, J., Votava, F., Marschalek, R., Stary, J., & Trka, J.

Acute leukemias with ETV6/ABL1 (TEL/ABL) fusion: poor prognosis and prenatal origin

Genes Chromosomes Cancer (2010), 49(10), 873-884

 

Kanderova, V., Hrusak, O., & Kalina, T.

Aberrantly expressed CEACAM6 is involved in the signaling leading to apoptosis of acute lymphoblastic leukemia cells

Exp Hematol (2010), 38(8), 653-660 e651

 

Mejstrikova, E., Fronkova, E., Kalina, T., Omelka, M., Batinic, D., Dubravcic, K., Pospisilova, K., Vaskova, M., Luria, D., Cheng, S. H., Ng, M., Leung, Y., Kappelmayer, J., Kiss, F., Izraeli, S., Stark, B., Schrappe, M., Trka, J., Stary, J., & Hrusak, O.

Detection of residual B precursor lymphoblastic leukemia by uniform gating flow cytometry

Pediatr Blood Cancer (2010) Jan;54(1):62-70.

 

Mejstrikova, E., Volejnikova, J., Fronkova, E., Zdrahalova, K., Kalina, T., Sterba, J., Jabali, Y., Mihal, V., Blazek, B., Cerna, Z., Prochazkova, D., Hak, J., Zemanova, Z., Jarosova, M., Oltova, A., Sedlacek, P., Schwarz, J., Zuna, J., Trka, J., Stary, J., & Hrusak, O.

Prognosis of children with mixed phenotype acute leukemia treated in accordance with consistent immunophenotypic criteria

Haematologica (2010) Jun;95(6):928-35. Epub 2010 Feb 9.

 

Dekking, E., van der Velden, V. H., Bottcher, S., Bruggemann, M., Sonneveld, E., Koning-Goedheer, A., Boeckx, N., Lucio, P., Sedek, L., Szczepanski, T., Kalina, T., Kovac, M., Evans, P., Hoogeveen, P. G., Flores-Montero, J., Orfao, A., Comans-Bitter, W. M., Staal, F. J., & van Dongen, J. J.

Detection of fusion genes at the protein level in leukemia patients via the flow cytometric immunobead assay

Best Pract Res Clin Haematol (2010), 23(3), 333-345

 

Pachlopnik Schmid, J., Canioni, D., Moshous, D., Touzot, F., Mahlaoui, N., Hauck, F., Kanegane, H., Lopez-Granados, E., Mejstrikova, E., Pellier, I., Galicier, L., Galambrun, C., Barlogis, V., Bordigoni, P., Fourmaintraux, A., Hamidou, M., Dabadie, A., Le Deist, F., Haerynck, F., Ouachee-Chardin, M., Rohrlich, P., Stephan, J. L., Lenoir, C., Rigaud, S., Lambert, N., Milili, M., Schiff, C., Chapel, H., Picard, C., de Saint Basile, G., Blanche, S., Fischer, A., & Latour, S.

Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency)

Blood (2011), 117(5), 1522-1529

 

Harrison, C. J., Haas, O., Harbott, J., Biondi, A., Stanulla, M., Trka, J., & Izraeli, S.

Detection of prognostically relevant genetic abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfurt-Munster study group

Br J Haematol (2010), 151(2), 132-142

 

Lizcova, L., Zemanova, Z., Malinova, E., Jarosova, M., Mejstrikova, E., Smisek, P., Pospisilova, D., Stary, J., & Michalova, K.

A novel recurrent chromosomal aberration involving chromosome 7 in childhood myelodysplastic syndrome

Cancer Genet Cytogenet, (2010) 201(1), 52-56

 

Lemez, P., Attarbaschi, A., Bene, M. C., Bertrand, Y., Castoldi, G., Forestier, E., Garand, R., Haas, O. A., Kagialis-Girard, S., Ludwig, W. D., Matutes, E., Mejstrikova, E., Pages, M. P., Pickl, W., Porwit, A., Orfao, A., Schabath, R., Stary, J., Strobl, H., Talmant, P., van't Veer, M. B., & Zemanova, Z.

Childhood near-tetraploid acute lymphoblastic leukemia: an EGIL study on 36 cases

Eur J Haematol (2010), 85(4), 300-308

 

Hollink, I. H., van den Heuvel-Eibrink, M. M., Zimmermann, M., Balgobind, B. V., Arentsen-Peters, S. T., Alders, M., Willasch, A., Kaspers, G. J., Trka, J., Baruchel, A., Creutzig, U., Pieters, R., Reinhardt, D., & Zwaan, C. M.

No Prognostic Impact of the WT1 Gene Single Nucleotide Polymorphism rs16754 in Pediatric Acute Myeloid Leukemia

J Clin Oncol

 

Stary, J., Jabali, Y., Trka, J., Hrusak, O., Gajdos, P., Hrstkova, H., Sterba, J., Blazek, B., Hak, J., Prochazkova, D., Cerna, Z., Smisek, P., Sedlacek, P., Vavra, V., Mihal, V., & Hrodek, O.

Long-term results of treatment of childhood acute lymphoblastic leukemia in the Czech Republic

Leukemia (2010), 24(2), 425-428

 

Lysak, D., Kalina, T., Martinek, J., Pikalova, Z., Vokurkova, D., Jaresova, M., Marinov, I., Ondrejkova, A., Spacek, M., & Stehlikova, O.

Interlaboratory variability of CD34+ stem cell enumeration. A pilot study to national external quality assessment within the Czech Republic

Int J Lab Hematol (2010), 32(6 Pt 1), e229-236

 

Gefen, N., Binder, V., Zaliova, M., Linka, Y., Morrow, M., Novosel, A., Edry, L., Hertzberg, L., Shomron, N., Williams, O., Trka, J., Borkhardt, A., & Izraeli, S.

Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53

Leukemia (2010), 24(1), 89-96

 

Balgobind, B. V., Lugthart, S., Hollink, I. H., Arentsen-Peters, S. T., van Wering, E. R., de Graaf, S. S., Reinhardt, D., Creutzig, U., Kaspers, G. J., de Bont, E. S., Stary, J., Trka, J., Zimmermann, M., Beverloo, H. B., Pieters, R., Delwel, R., Zwaan, C. M., & van den Heuvel-Eibrink, M. M.

EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemia

Leukemia (2010), 24(5), 942-949

 

2009

Kalina, T., Stuchly, J., Janda, A., Hrusak, O., Ruzickova, S., Sediva, A., Litzman, J., & Vlkova, M.

Profiling of polychromatic flow cytometry data on B-cells reveals patients' clusters in common variable immunodeficiency

Cytometry A (2009), 75A(11), 902-909

 

Zuna, J., Prouzova, Z., Kalina, T., Lizcova, L., Zemanova, Z., Muzikova, K., Rahmatova, S., Meijerink, J. P., & Trka, J.

Backtracking of ALL to cord blood

Leuk Res (2009), 33(8), e107-108

 

Zuna, J., Burjanivova, T., Mejstrikova, E., Zemanova, Z., Muzikova, K., Meyer, C., Horsley, S. W., Kearney, L., Colman, S., Ptoszkova, H., Marschalek, R., Hrusak, O., Stary, J., Greaves, M., & Trka, J.

Covert preleukemia driven by MLL gene fusion

Genes Chromosomes Cancer (2009), 48(1), 98-107

 

Zaliova, M., Fronkova, E., Krejcikova, K., Muzikova, K., Mejstrikova, E., Stary, J., Trka, J., & Zuna, J.

Quantification of fusion transcript reveals a subgroup with distinct biological properties and predicts relapse in BCR/ABL-positive ALL: implications for residual disease monitoring

Leukemia (2009), 23(5), 944-951

 

Svojgr, K., Burjanivova, T., Vaskova, M., Kalina, T., Stary, J., Trka, J., & Zuna, J.

Adaptor molecules expression in normal lymphopoiesis and in childhood leukemia

Immunol Lett (2009), 122(2), 185-192

 

Willasch, A. M., Gruhn, B., Coliva, T., Kalinova, M., Schneider, G., Kreyenberg, H., Steinbach, D., Weber, G., Hollink, I. H., Zwaan, C. M., Biondi, A., van der Velden, V. H., Reinhardt, D., Cazzaniga, G., Bader, P., & Trka, J.

Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study

Leukemia (2009), 23(8), 1472-1479

 

Weerkamp, F., Dekking, E., Ng, Y. Y., van der Velden, V. H., Wai, H., Bottcher, S., Bruggemann, M., van der Sluijs, A. J., Koning, A., Boeckx, N., Van Poecke, N., Lucio, P., Mendonca, A., Sedek, L., Szczepanski, T., Kalina, T., Kovac, M., Hoogeveen, P. G., Flores-Montero, J., Orfao, A., Macintyre, E., Lhermitte, L., Chen, R., Brouwer-De Cock, K. A., van der Linden, A., Noordijk, A. L., Comans-Bitter, W. M., Staal, F. J., & van Dongen, J. J.

Flow cytometric immunobead assay for the detection of BCR-ABL fusion proteins in leukemia patients

Leukemia (2009), 23(6), 1106-1117

 

Meyer, C., Kowarz, E., Hofmann, J., Renneville, A., Zuna, J., Trka, J., Ben Abdelali, R., Macintyre, E., De Braekeleer, E., De Braekeleer, M., Delabesse, E., de Oliveira, M. P., Cave, H., Clappier, E., van Dongen, J. J., Balgobind, B. V., van den Heuvel-Eibrink, M. M., Beverloo, H. B., Panzer-Grumayer, R., Teigler-Schlegel, A., Harbott, J., Kjeldsen, E., Schnittger, S., Koehl, U., Gruhn, B., Heidenreich, O., Chan, L. C., Yip, S. F., Krzywinski, M., Eckert, C., Moricke, A., Schrappe, M., Alonso, C. N., Schafer, B. W., Krauter, J., Lee, D. A., Zur Stadt, U., Te Kronnie, G., Sutton, R., Izraeli, S., Trakhtenbrot, L., Lo Nigro, L., Tsaur, G., Fechina, L., Szczepanski, T., Strehl, S., Ilencikova, D., Molkentin, M., Burmeister, T., Dingermann, T., Klingebiel, T., & Marschalek, R.

New insights to the MLL recombinome of acute leukemias

Leukemia (2009), 23(8), 1490-1499

 

Horvath, R., Budinsky, V., Kayserova, J., Kalina, T., Formankova, R., Stary, J., Bartunkova, J., Sedlacek, P., & Spisek, R.

Kinetics of dendritic cells reconstitution and costimulatory molecules expression after myeloablative allogeneic haematopoetic stem cell transplantation: implications for the development of acute graft-versus host disease

Clin Immunol (2009), 131(1), 60-69

 

Hollink, I. H., van den Heuvel-Eibrink, M. M., Zimmermann, M., Balgobind, B. V., Arentsen-Peters, S. T., Alders, M., Willasch, A., Kaspers, G. J., Trka, J., Baruchel, A., de Graaf, S. S., Creutzig, U., Pieters, R., Reinhardt, D., & Zwaan, C. M.

Clinical relevance of Wilms tumor 1 gene mutations in childhood acute myeloid leukemia

Blood (2009), 113(23), 5951-5960

 

2008

Vaskova, M., Fronkova, E., Starkova, J., Kalina, T., Mejstrikova, E., & Hrusak, O.

CD44 and CD27 delineate B-precursor stages with different recombination status and with an uneven distribution in nonmalignant and malignant hematopoiesis

Tissue Antigens (2008), 71(1), 57-66

 

Smetana, K., Zapotocky, M., Starkova, J., & Trka, J.

To the nucleolar density and size in apoptotic human leukemic myeloblasts produced in vitro by Trichostatin A

Eur J Histochem (2008), 52(3), 143-148

 

Krol, L., Formankova, R., Keslova, P., Vavra, V., Zemanova, Z., Michalova, K., Dobrovolna, M., Moravcova, J., Kobylka, P., Ivaskova, E., Navratilova, J., Stary, J., & Sedlacek, P.

Prognosis of pediatric patients transplanted for Ph+ chronic myeloid leukemia in the period from 1989 to 2006 in the Czech Republic

Neoplasma (2008), 55(2), 101-106

 

Fronkova, E., Muzikova, K., Mejstrikova, E., Kovac, M., Formankova, R., Sedlacek, P., Hrusak, O., Stary, J., & Trka, J.

B-cell reconstitution after allogeneic SCT impairs minimal residual disease monitoring in children with ALL

Bone Marrow Transplant (2008), 42(3), 187-196

 

Fronkova, E., Mejstrikova, E., Avigad, S., Chik, K. W., Castillo, L., Manor, S., Reznickova, L., Valova, T., Zdrahalova, K., Hrusak, O., Jabali, Y., Schrappe, M., Conter, V., Izraeli, S., Li, C. K., Stark, B., Stary, J., & Trka, J.

Minimal residual disease (MRD) analysis in the non-MRD-based ALL IC-BFM 2002 protocol for childhood ALL: is it possible to avoid MRD testing?

Leukemia (2008), 22(5), 989-997

 

Metzler, M., Staege, M. S., Harder, L., Mendelova, D., Zuna, J., Fronkova, E., Meyer, C., Flohr, T., Bednarova, D., Harbott, J., Langer, T., Gesk, S., Trka, J., Siebert, R., Dingermann, T., Marschalek, R., Niemeyer, C., & Rascher, W.

Inv(11)(q21q23) fuses MLL to the Notch co-activator mastermind-like 2 in secondary T-cell acute lymphoblastic leukemia

Leukemia (2008), 22(9), 1807-1811

 

Kerst, G., Bergold, N., Gieseke, F., Coustan-Smith, E., Lang, P., Kalinova, M., Handgretinger, R., Trka, J., & Muller, I.

WT1 protein expression in childhood acute leukemia

Am J Hematol (2008), 83(5), 382-386

 

Bercovich, D., Ganmore, I., Scott, L. M., Wainreb, G., Birger, Y., Elimelech, A., Shochat, C., Cazzaniga, G., Biondi, A., Basso, G., Cario, G., Schrappe, M., Stanulla, M., Strehl, S., Haas, O. A., Mann, G., Binder, V., Borkhardt, A., Kempski, H., Trka, J., Bielorei, B., Avigad, S., Stark, B., Smith, O., Dastugue, N., Bourquin, J. P., Tal, N. B., Green, A. R., & Izraeli, S.

Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

Lancet (2008), 372(9648), 1484-1492

 

2007

Zuna, J., Cave, H., Eckert, C., Szczepanski, T., Meyer, C., Mejstrikova, E., Fronkova, E., Muzikova, K., Clappier, E., Mendelova, D., Boutard, P., Schrauder, A., Sterba, J., Marschalek, R., van Dongen, J. J., Hrusak, O., Stary, J., & Trka, J.

Childhood secondary ALL after ALL treatment

Leukemia (2007), 21(7), 1431-1435

 

Starkova, J., Madzo, J., Cario, G., Kalina, T., Ford, A., Zaliova, M., Hrusak, O., & Trka, J.

The identification of (ETV6)/RUNX1-regulated genes in lymphopoiesis using histone deacetylase inhibitors in ETV6/RUNX1-positive lymphoid leukemic cells

Clin Cancer Res (2007), 13(6), 1726-1735

 

Sramkova, L., Muzikova, K., Fronkova, E., Krejci, O., Sedlacek, P., Formankova, R., Mejstrikova, E., Stary, J., & Trka, J.

Detectable minimal residual disease before allogeneic hematopoietic stem cell transplantation predicts extremely poor prognosis in children with acute lymphoblastic leukemia

Pediatr Blood Cancer (2007), 48(1), 93-100

 

Smetana, K., Zapotocky, M., Starkova, J., & Trka, J.

Effect of histone deacetylase inhibitors on the cell nucleus and nucleolus of leukemic myeloblasts in vitro - A cytochemical study

Acta Histochem (2007)

 

Smetana, K., Kuzelova, K., Zapotocky, M., Starkova, J., Hrkal, Z., & Trka, J.

Mean diameter of nucleolar bodies in cultured human leukemic myeloblasts is mainly related to the S and G2 phase of the cell cycle

Eur J Histochem (2007), 51(4), 269-274

 

Janda, A., Sedlacek, P., Mejstrikova, E., Zdrahalova, K., Hrusak, O., Kalina, T., Sieglova, Z., Zizkova, H., Formankova, R., Keslova, P., Hubacek, P., Sediva, A., Bartunkova, J., Dlask, K., & Stary, J.

Unrelated partially matched lymphocyte infusions in a patient with complete DiGeorge/CHARGE syndrome

Pediatr Transplant (2007), 11(4), 441-447

 

Hubacek, P., Hyncicova, K., Muzikova, K., Cinek, O., Zajac, M., & Sedlacek, P.

Disappearance of pre-existing high HHV-6 DNA load in blood after allogeneic SCT

Bone Marrow Transplant (2007), 40(8), 805-806

 

van der Velden, V. H., Cazzaniga, G., Schrauder, A., Hancock, J., Bader, P., Panzer-Grumayer, E. R., Flohr, T., Sutton, R., Cave, H., Madsen, H. O., Cayuela, J. M., Trka, J., Eckert, C., Foroni, L., Zur Stadt, U., Beldjord, K., Raff, T., van der Schoot, C. E., & van Dongen, J. J.

Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data

Leukemia (2007), 21(4), 604-611

 

Hagedorn, N., Acquaviva, C., Fronkova, E., von Stackelberg, A., Barth, A., zur Stadt, U., Schrauder, A., Trka, J., Gaspar, N., Seeger, K., Henze, G., Cave, H., & Eckert, C.

Submicroscopic bone marrow involvement in isolated extramedullary relapses in childhood acute lymphoblastic leukemia: a more precise definition of "isolated" and its possible clinical implications, a collaborative study of the Resistant Disease Committee of the International BFM study group

Blood (2007), 110(12), 4022-4029

 

2006

Vaskova, M., Mejstrikova, E., Kalina, T., Trka, J., Stary, J., & Hrusak, O.

CD27 expression in malignant and normal human B precursors: a confirmed phenomenon. Reply to Nilsson and colleagues

Exp Hematol (2006), 34(5), 573; author reply 574

 

Sedlacek, P., Formankova, R., Keslova, P., Sramkova, L., Hubacek, P., Krol, L., Kulich, M., & Stary, J.

Low mortality of children undergoing hematopoietic stem cell transplantation from 7 to 8/10 human leukocyte antigen allele-matched unrelated donors with the use of antithymocyte globulin

Bone Marrow Transplant (2006), 38(11), 745-750

 

Burjanivova, T., Madzo, J., Muzikova, K., Meyer, C., Schneider, B., Votava, F., Marschalek, R., Stary, J., Trka, J., & Zuna, J.

Prenatal origin of childhood AML occurs less frequently than in childhood ALL

BMC Cancer (2006), 6, 100

 

Boublikova, L., Kalinova, M., Ryan, J., Quinn, F., O'Marcaigh, A., Smith, O., Browne, P., Stary, J., McCann, S. R., Trka, J., & Lawler, M.

Wilms' tumor gene 1 (WT1) expression in childhood acute lymphoblastic leukemia: a wide range of WT1 expression levels, its impact on prognosis and minimal residual disease monitoring

Leukemia (2006), 20(2), 254-263

 

Wunderlich, M., Krejci, O., Wei, J., & Mulloy, J. C.

Human CD34+ cells expressing the inv(16) fusion protein exhibit a myelomonocytic phenotype with greatly enhanced proliferative ability

Blood (2006), 108(5), 1690-1697

 

Meyer, C., Schneider, B., Jakob, S., Strehl, S., Attarbaschi, A., Schnittger, S., Schoch, C., Jansen, M. W., van Dongen, J. J., den Boer, M. L., Pieters, R., Ennas, M. G., Angelucci, E., Koehl, U., Greil, J., Griesinger, F., Zur Stadt, U., Eckert, C., Szczepanski, T., Niggli, F. K., Schafer, B. W., Kempski, H., Brady, H. J., Zuna, J., Trka, J., Nigro, L. L., Biondi, A., Delabesse, E., Macintyre, E., Stanulla, M., Schrappe, M., Haas, O. A., Burmeister, T., Dingermann, T., Klingebiel, T., & Marschalek, R.

The MLL recombinome of acute leukemias

Leukemia (2006), 20(5), 777-784

 

Langebrake, C., Creutzig, U., Dworzak, M., Hrusak, O., Mejstrikova, E., Griesinger, F., Zimmermann, M., & Reinhardt, D.

Residual disease monitoring in childhood acute myeloid leukemia by multiparameter flow cytometry: the MRD-AML-BFM Study Group

J Clin Oncol (2006), 24(22), 3686-3692

 

2005 a dříve

Zuna, J., Krejci, O., Madzo, J., Fronkova, E., Sramkova, L., Hrusak, O., Kalina, T., Vaskova, M., Stary, J., & Trka, J.

TEL/AML1 and immunoreceptor gene rearrangements-which comes first?

Leuk Res (2005), 29(6), 633-639

 

Vaskova, M., Mejstrikova, E., Kalina, T., Martinkova, P., Omelka, M., Trka, J., Stary, J., & Hrusak, O.

Transfer of genomics information to flow cytometry: expression of CD27 and CD44 discriminates subtypes of acute lymphoblastic leukemia

Leukemia (2005), 19(5), 876-878

 

Mejstrikova, E., Kalina, T., Trka, J., Stary, J., & Hrusak, O.

Correlation of CD33 with poorer prognosis in childhood ALL implicates a potential of anti-CD33 frontline therapy

Leukemia (2005), 19(6), 1092-1094

 

Kalina, T., Vaskova, M., Mejstrikova, E., Madzo, J., Trka, J., Stary, J., & Hrusak, O.

Myeloid antigens in childhood lymphoblastic leukemia: clinical data point to regulation of CD66c distinct from other myeloid antigens

BMC Cancer (2005), 5(1), 38

 

Kalina, T., Lu, H., Zhao, Z., Blewett, E., Dittmer, D. P., Randolph-Habecker, J., Maloney, D. G., Andrews, R. G., Kiem, H. P., & Storek, J.

De novo generation of CD4 T cells against viruses present in the host during immune reconstitution

Blood (2005), 105(6), 2410-2414

 

Fronkova, E., Madzo, J., Zuna, J., Reznickova, L., Muzikova, K., Hrusak, O., Stary, J., & Trka, J.

TEL/AML 1 real-time quantitative reverse transcriptase PCR can complement minimal residual disease assessment in childhood ALL

Leukemia (2005), 19(7), 1296-1297

 

Fronkova, E., Krejci, O., Kalina, T., Horvath, O., Trka, J., & Hrusak, O.

Lymphoid differentiation pathways can be traced by TCR delta rearrangements

J Immunol (2005), 175(4), 2495-2500

 

Sediva, A., Bartunkova, J., Zachova, R., Polouckova, A., Hrusak, O., Janda, A., Kocarek, E., Novotna, D., Novotna, K., & Klein, T.

Early development of immunity in diGeorge syndrome

Med Sci Monit (2005), 11(4), CR182-187

 

Mulloy, J. C., Jankovic, V., Wunderlich, M., Delwel, R., Cammenga, J., Krejci, O., Zhao, H., Valk, P. J., Lowenberg, B., & Nimer, S. D.

AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34+ cells, allowing nerve growth factor-induced expansion

Proc Natl Acad Sci U S A (2005), 102(11), 4016-4021

 

Lu, H., Zhao, Z., Kalina, T., Gillespy, T., 3rd, Liggitt, D., Andrews, R. G., Maloney, D. G., Kiem, H. P., & Storek, J.

Interleukin-7 improves reconstitution of antiviral CD4 T cells

Clin Immunol (2005), 114(1), 30-41

 

Zuna, J., Ford, A. M., Peham, M., Patel, N., Saha, V., Eckert, C., Kochling, J., Panzer-Grumayer, R., Trka, J., & Greaves, M.

TEL deletion analysis supports a novel view of relapse in childhood acute lymphoblastic leukemia

Clin Cancer Res (2004), 10(16), 5355-5360

 

Krejci, O., Starkova, J., Otova, B., Madzo, J., Kalinova, M., Hrusak, O., & Trka, J.

Upregulation of asparagine synthetase fails to avert cell cycle arrest induced by L-asparaginase in TEL/AML1-positive leukaemic cells

Leukemia (2004), 18(3), 434-441

 

Storek, J., Zhao, Z., Lin, E., Berger, T., McSweeney, P. A., Nash, R. A., Akatsuka, Y., Metcalf, M. D., Lu, H., Kalina, T., Reindl, M., Storb, R., Hansen, J. A., Sullivan, K. M., Kraft, G. H., Furst, D. E., & Maloney, D. G.

Recovery from and consequences of severe iatrogenic lymphopenia (induced to treat autoimmune diseases)

Clin Immunol (2004), 113(3), 285-298

 

Kracht, T., Schrappe, M., Strehl, S., Reiter, A., Elsner, H. A., Trka, J., Cario, G., Viehmann, S., Harbott, J., Borkhardt, A., Metzler, M., Langer, T., Repp, R., Marschalek, R., Welte, K., Haas, O. A., & Stanulla, M.

NQO1 C609T polymorphism in distinct entities of pediatric hematologic neoplasms

Haematologica (2004), 89(12), 1492-1497

 

Zuna, J., Muzikova, K., Ford, A. M., Maia, A. T., Krejci, O., Tousovska, K., Oravkinova, I., Greaves, M., & Trka, J.

Pre-natal, clonal origin of acute lymphoblastic leukaemia in triplets

Leuk Lymphoma (2003), 44(12), 2099-2102

 

Madzo, J., Zuna, J., Muzikova, K., Kalinova, M., Krejci, O., Hrusak, O., Otova, B., Stary, J., & Trka, J.

Slower molecular response to treatment predicts poor outcome in patients with TEL/AML1 positive acute lymphoblastic leukemia: prospective real-time quantitative reverse transcriptase-polymerase chain reaction study

Cancer (2003), 97(1), 105-113

 

Krejci, O., van der Velden, V. H., Bader, P., Kreyenberg, H., Goulden, N., Hancock, J., Schilham, M. W., Lankester, A., Revesz, T., Klingebiel, T., & van Dongen, J. J.

Level of minimal residual disease prior to haematopoietic stem cell transplantation predicts prognosis in paediatric patients with acute lymphoblastic leukaemia: a report of the Pre-BMT MRD Study Group

Bone Marrow Transplant (2003), 32(8), 849-851

 

Rainis, L., Bercovich, D., Strehl, S., Teigler-Schlegel, A., Stark, B., Trka, J., Amariglio, N., Biondi, A., Muler, I., Rechavi, G., Kempski, H., Haas, O. A., & Izraeli, S.

Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21

Blood (2003), 102(3), 981-986

 

Goulden, N., Bader, P., Van Der Velden, V., Moppett, J., Schilham, M., Masden, H. O., Krejci, O., Kreyenberg, H., Lankester, A., Revesz, T., Klingebiel, T., & Van Dongen, J.

Minimal residual disease prior to stem cell transplant for childhood acute lymphoblastic leukaemia

Br J Haematol (2003), 122(1), 24-29

 

Zuna, J., Muzikova, K., Madzo, J., Krejci, O., & Trka, J.

Temperature non-homogeneity in rapid airflow-based cycler significantly affects real-time PCR

Biotechniques (2002), 33(3), 508, 510, 512

 

Zuna, J., Muzikova, K., Hrusak, O., Stary, J., & Trka, J.

Significance of real-time quantitative PCR detection of p16 gene deletions in childhood acute lymphoblastic leukemia

Haematologica (2002), 87(6), 668-669

 

Trka, J., Kalinova, M., Hrusak, O., Zuna, J., Krejci, O., Madzo, J., Sedlacek, P., Vavra, V., Michalova, K., Jarosova, M., & Stary, J.

Real-time quantitative PCR detection of WT1 gene expression in children with AML: prognostic significance, correlation with disease status and residual disease detection by flow cytometry

Leukemia (2002), 16(7), 1381-1389

 

Stary, J., Gajdos, P., Hrstkova, H., Blazek, B., Slavik, Z., Mihal, V., Zahalka, F., Jabali, Y., Vavra, V., Kopecna, L., Mydlil, J., & Trka, J.

Treatment of Czech children with acute lymphoblastic leukemia: a report of the Czech Working Group for Pediatric Hematology

Med Pediatr Oncol (2002), 39(2), 125-127

 

Hrusak, O., Trka, J., Zuna, J., Polouckova, A., Kalina, T., & Stary, J.

Acute lymphoblastic leukemia incidence during socioeconomic transition: selective increase in children from 1 to 4 years

Leukemia (2002), 16(4), 720-725

 

Hrusak, O., & Porwit-MacDonald, A.

Antigen expression patterns reflecting genotype of acute leukemias

Leukemia (2002), 16(7), 1233-1258

 

Reinhardt, D., Langebrake, C., Creutzig, U., Vormoor, J., Brune, C., Thorwesten, M., Ingiliz, P., Hrusak, O., Dworzak, M., & Griesinger, F.

[Minimal residual disease in acute myeloid leukemia in children--standardization and evaluation of immunophenotyping in the AML-BFM-98 study]

Klin Padiatr (2002), 214(4), 179-187

 

Jarosova, M., Holzerova, M., Mihal, V., Blatny, J., Lakoma, I., Trka, J., Pikalova, Z., Hrusak, O., & Indrak, K.

Additional evidence of genetic changes in children with ALL and TEL/AML1 fusion gene

Leukemia (2002), 16(9), 1873-1875

 

Seeger, K., Viehmann, S., Buchwald, D., Harbott, J., Schrappe, M., Stary, J., Henze, G., & Trka, J.

Treatment response and residual-disease monitoring in initial and relapsed TEL-AML1 positive childhood ALL

Leukemia (2001), 15(2), 280-282

 

Sedlacek, P., Trka, J., Zuna, J., Hrusak, O., Honzatkova-Krskova, L., & Stary, J.

Monitoring of minimal residual disease and mixed chimerism in a case of high-risk TEL/AML1+ acute lymphoblastic leukemia pre- and post-bone marrow transplantation. Czech Pediatric Haematology Working Group

Haematologica (2000), 85(10), 1100-1102

 

Myers, R. S., Ball, K. K., Kalina, T. D., Roth, D. L., & Goode, K. T.

Relation of useful field of view and other screening tests to on-road driving performance

Percept Mot Skills (2000), 91(1), 279-290

 

Zuna, J., Hrusak, O., Kalinova, M., Muzikova, K., Stary, J., & Trka, J.

TEL/AML1 positivity in childhood ALL: average or better prognosis? Czech Paediatric Haematology Working Group

Leukemia (1999), 13(1), 22-24

 

Zuna, J., Hrusak, O., Kalinova, M., Muzikova, K., Stary, J., & Trka, J.

Significantly lower relapse rate for TEL/AML1-positive ALL

Leukemia (1999), 13(10), 1633

 

Trka, J., Zuna, J., Hrusak, O., Michalova, K., Muzikova, K., Kalinova, M., Horak, J., & Stary, J.

No evidence for MLL/AF4 expression in normal cord blood samples

Blood (1999), 93(3), 1106-1107; author reply 1108-1110

 

Hrusak, O., Trka, J., Zuna, J., Bartunkova, J., & Stary, J.

Are we ready to curtail testing for TEL/AML1 fusion? Pediatric Hematology Working Group in the Czech Republic

Leukemia (1999), 13(6), 981-983

 

Trka, J., Zuna, J., Hrusak, O., Kalinova, M., Muzikova, K., Lauschman, H., & Stary, J.

Impact of TEL/AML1-positive patients on age distribution of childhood acute lymphoblastic leukemia in Czech Republic. Pediatric Hematology Working Group in Czech Republic

Leukemia (1998), 12(6), 996-997

 

Hrusak, O., Trka, J., Zuna, J., Houskova, J., Bartunkova, J., & Stary, J.

Aberrant expression of KOR-SA3544 antigen in childhood acute lymphoblastic leukemia predicts TEL-AML1 negativity. The Pediatric Hematology Working Group in the Czech Republic

Leukemia (1998), 12(7), 1064-1070

 

Eckschlager, T., Pilat, D., Kodet, R., Dahbiova, R., Stankova, J., Jasinska, J., & Hrusak, O.

DNA ploidy in neuroblastoma

Neoplasma (1996), 43(1), 23-26

 

Trka, J., Divoky, V., & Lion, T.

Prevention of product carry-over by single tube two-round (ST-2R) PCR: application to BCR-ABL analysis in chronic myelogenous leukemia

Nucleic Acids Res (1995), 23(22), 4736-4737

 

Eckschlager, T., Pilat, D., Kodet, R., Stary, J., Jasinska, J., & Hrusak, O.

[DNA cytometry analysis in childhood tumors]

Cas Lek Cesk (1995), 134(10), 302-305

Vytvořeno: 2. 2. 2022 / Upraveno: 5. 9. 2022 / Odpovědná osoba: Administrátor