CLIP - Childhood Leukaemia Investigation Prague

Scientific News

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Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia. Zeisig BB, Fung TK, Zarowiecki M, Tsai CT, Luo H, Stanojevic B, Lynn C, Leung AYH, Zuna J, Zaliova M, Bornhauser M, von Bonin M, Lenhard B, Huang S, Mufti GJ, So CWE. Sci Transl Med. 2021 Feb 24;13(582):eabc4822. 

                                                                                        


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Potential and pitfalls of whole transcriptome-based immunogenetic marker identification in acute lymphoblastic leukemia; a EuroMRD and EuroClonality-NGS Working Group study. van der Velden VHJ, Brüggemann M, Cazzaniga G, Scheijen B, Tops B, Trka J, Pal K, Hänzelmann S, Fazio G, Songia S, Langerak AW, Darzentas N; EuroMRD; EuroClonality-NGS Working Group. Leukemia. 2021 Mar;35(3):924-928. 


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Identification of Fusion Gene Breakpoints is Feasible and Facilitates Accurate Sensitive Minimal Residual Disease Monitoring on Genomic Level in Patients With PML-RARA, CBFB-MYH11, and RUNX1-RUNX1T1. Lukes J Jr, Winkowska L, Zwyrtkova M, Starkova J, Sramkova L, Stary J, Trka J, Zuna J, Zaliova M. Hemasphere. 2020 Nov 10;4(6) 

                                                                                        

 

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