Programme

14 October (Tuesday)  
9:15 Registration (coffee available)
10:00–10:10 Opening
SESSION I chairs: Júlia Starková, David Sabatini
10:10–11:00

keynote speaker

Arkaitz Carracedo (CICbioGUNE, Bilbao)
Systemic and cellular metabolic influences in prostate cancer
11:00–11:25 Kristýna Gloc Pimková (First Faculty of Medicine, Charles University) 
Redox-driven proteome reprogramming underlies treatment resistance in myelodysplastic syndromes and acute myeloid leukemia
11:25–11:50 Štěpána Boukalová (Institute of Biotechnology, Czech Academy od Sciences)
Mitochondrial complex II deficiency in endocrine tumors: mechanisms and therapeutic opportunities
11:50–12:20 Coffee break
12:20–12:45 Kateřina Rohlenová (Institute of Biotechnology, Czech Academy od Sciences)
Consequences of pyrimidine synthesis deficiency in tumor environment
12:45–13:00 Petr Heneberg (Third Faculty of Medicine, Charles University)
Metabolic profiling of primary HGSOC cells refutes binary OXPHOS classification
13:00–13:15 Matuš Kolárik (Second Faculty of Medicine, Charles University)
L-Asparaginase as a redox regulator in leukemic cells
13:15–13:30 Kamila Baslarová (Institute of Physiology, Czech Academy od Sciences)
Metabolic changes in breast cancer cells: development of tamoxifen resistance
13:30–14:30 Lunch
SESSION II chair: Tomáš Mráček
14:30–14:55 Petra Holečková (Fakultní nemocnice Bulovka, Prague) 
Nutrition in oncology
14:55–15:10 Alexandra Dolníková (First Faculty of Medicine, Charles University)
Metabolic heterogeneity in lymphoproliferative disorders; Insights from preclinical lymphoma cell line studies
15:10–15:25 Jan Trnka (Third Faculty of Medicine, Charles University) 
Ribosome transfer via tunnelling nanotubes rescues protein synthesis in pancreatic cancer cells
15:25–15:40 Dušan Němec (First Faculty of Medicine)
Quantitative and redox proteomics analysis of signaling pathways triggered by
antioxidant metabolism disruption in leukemia drug-resistance
15:40–15:50

Poster pitch I

presenters: Hložková, Ormsby, Gumulec
15:50–16:10 Coffee break
16:10–17:20

Poster session I

chair: Jakub Rohlena
18:00–23:00 Social event Ladronka
15 October (Wednesday)  
SESSION III chair: Kateřina Rohlenová
9:15–10:05

keynote speaker

David Sabatini (IOCB Prague/Boston)
Regulation of Growth by the mTOR pathway
10:05–10:30 Ondřej Novák (Second Faculty fo Medicine, Charles University)
When epilepsy meets oncology – shared disease mechanisms
10:30–10:45 Ahmad Alghadi (Institute of Biotechnology, Czech Academy od Sciences)
Functional genomics reveals metabolic vulnerabilities in DHODH-inhibited non-small cell lung cancer
10:45–11:00 Jaromír Novák (Institute of Biotechnology, Czech Academy od Sciences)
Miro1 modulates horizontal transfer of mitochondria in mouse melanoma models
11:00–11:10

Poster pitch II

presenters: Nahacká, Burda
11:10–11:35 Coffee break
11:35–12:45

Poster session II

chair: Jaroslav Truksa
12:45–13:45 Lunch
SESSION IV (IBT) chair: Ladislav Anděra
13:45–14:10 Francesca Mateinni (IDIBELL, Barcelona)
A Notch trans-activation to cis-inhibition switch underlies hematopoietic stem cell aging
14:10–14:35 Alena Pecinová (Institute of Physiology, Czech Academy od Sciences)
Sequestration of the polyunsaturated fatty acids protects the cells with oxidative phosphorylation deficiency from ferroptosis
14:35–15:00 Libor Macůrek (Institute of Biotechnology, Czech Academy od Sciences)
Targeting of cancers caused by truncating mutations of PPM1D phosphatase
15:00–15:25

Jaroslav Truksa (Institute of Biotechnology, Czech Academy od Sciences)
The Good, the Bad and the Ugly: mitochondria, tamoxifen resistance and cardiolipin
15:25–15:30 Closing
15:30–15:50 Coffee break
Vytvořeno: 25. 7. 2025 / Upraveno: 13. 10. 2025 / Odpovědná osoba: Administrátor